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Found 13 with Last Name = 'nilius' and Initial = 'b'
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataIC50:  9.20E+4nMAssay Description:Displacement of [3H]menthol from human TRPM8 expressed in HEK293 cell membranes by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataEC50:  2.90E+4nMAssay Description:Activity at human TRPM8 expressed in HEK293 cells assessed as compound concentration causing leftward shift of voltage for half maximal activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM50277489(4alpha-Phorbol 12,13-dinonanoate | CHEMBL130626)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50277740(4-Deoxy-4alpha-Phorbol 12,13-didecanoate | CHEMBL5...)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50277487(4alpha-Phorbol 12,13-dihexanoate | CHEMBL490470)
Affinity DataEC50:  70nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50277488(4alpha-Phorbol 12,13-dioctanoate | CHEMBL507303)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50240777(4alpha-phorbol-didecanoate | CHEMBL118987 | Decano...)
Affinity DataEC50:  370nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
LigandPNGBDBM50277486(4alpha-Phorbol 13-decanoate | CHEMBL541720)
Affinity DataEC50:  450nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50277490(4alpha-Phorbol 12,13-dimyristate | CHEMBL451849)
Affinity DataEC50:  2.83E+3nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataEC50:  2.25E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50277739(4alpha-phorbol diacetate | CHEMBL484343)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50318482((-)-menthol | CHEMBL470670 | MENTHOL | US11406649,...)
Affinity DataKd:  1.44E+4nMAssay Description:Binding affinity to human TRPM8 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM50277491(CHEMBL504955 | Lumi-4alpha-Phorbol 12,13-didecanoa...)
Affinity DataEC50:  175nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed