Compile Data Set for Download or QSAR
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Found 13 with Last Name = 'nirogia' and Initial = 'rv'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234385(2-Methoxy-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4b...)
Affinity DataKi:  127nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234384(2-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataKi:  464nM ΔG°:  -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234386(1-Fluoro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataKi: >500nM ΔG°: >-37.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50:  5.06E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50:  7.65E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50:  3.71E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >4.50E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed