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Found 163 with Last Name = 'noble' and Initial = 'f'
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50449787(CHEMBL2062154 | PD-134308)
Affinity DataKi:  0.400nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50061266((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity (affinity state 1) for Cholecystokinin type B receptor, was determined using CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087104(C-{[3-Biphenyl-4-yl-2-(carboxymethyl-carbamoyl)-pr...)
Affinity DataKi:  0.940nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087106((2S)-2-[(2S)-3-{[(1S)-1-azaniumylethyl](hydroxy)ph...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105262(2-{3-[(1-Amino-ethyl)-hydroxy-phosphinoyl]-2-biphe...)
Affinity DataKi:  1.20nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087088((2S)-2-[(2S)-3-[(1-azaniumylethyl)(hydroxy)phospho...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087089((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataKi:  1.70nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087095(1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50061270((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity (affinity state 1) for Cholecystokinin type B receptor, was determined using CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105263(2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105261(1-[2-(1-Benzyloxycarbonyl-2-phenyl-ethylcarbamoyl)...)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087113((2S)-2-[(2S)-3-{[(S)-azaniumyl(phenyl)methyl](hydr...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM81962(S-L-365,260)
Affinity DataKi:  2nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087085((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...)
Affinity DataKi:  2.20nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087097(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  2.20nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087084(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087085((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087093(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087094((R,S,S)1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4...)
Affinity DataKi:  2.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087100((2S)-2-[(2S)-3-{[azaniumyl(phenyl)methyl](hydroxy)...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105262(2-{3-[(1-Amino-ethyl)-hydroxy-phosphinoyl]-2-biphe...)
Affinity DataKi:  2.90nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, aminopeptidase N(APN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087106((2S)-2-[(2S)-3-{[(1S)-1-azaniumylethyl](hydroxy)ph...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087089((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087114(C-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  3.10nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087096(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  3.20nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087101(1-{[3-Biphenyl-4-yl-2-(1-carboxy-propylcarbamoyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087105(1-{[3-Biphenyl-4-yl-2-(1-carboxy-2-phenyl-ethylcar...)
Affinity DataKi:  3.70nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087111((2S)-2-[(2S)-3-{[(S)-azaniumyl(phenyl)methyl](hydr...)
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087098((2S)-2-[(2S)-3-{[azaniumyl(phenyl)methyl](hydroxy)...)
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087094((R,S,S)1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4...)
Affinity DataKi:  4.60nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105263(2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...)
Affinity DataKi:  4.80nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, aminopeptidase N(APN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087113((2S)-2-[(2S)-3-{[(S)-azaniumyl(phenyl)methyl](hydr...)
Affinity DataKi:  4.80nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087095(1-{[3-(4-Bromo-phenyl)-2-(1-carboxy-ethylcarbamoyl...)
Affinity DataKi:  4.90nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087119(C-{[3-Biphenyl-4-yl-2-(1-carboxy-2-hydroxy-ethylca...)
Affinity DataKi:  4.90nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087088((2S)-2-[(2S)-3-[(1-azaniumylethyl)(hydroxy)phospho...)
Affinity DataKi:  5.20nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087085((2S)-2-[(2S)-3-{[(1S)-1-azaniumyl-2-phenylethyl](h...)
Affinity DataKi:  5.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50061276((R)-1-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1...)
Affinity DataKi:  6.10nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087109(1-{[3-Biphenyl-4-yl-2-(1-carboxy-3-methyl-butylcar...)
Affinity DataKi:  6.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087112(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Affinity DataKi:  6.30nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087102(1-{[2-(1-Carboxy-3-methyl-butylcarbamoyl)-3-phenyl...)
Affinity DataKi:  6.40nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50061267((2R,4R)-1-[(R)-2-(2-Aza-tricyclo[3.3.1.1*3,7*]dec-...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity (affinity state 1) for Cholecystokinin type B receptor, was determined using CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50449787(CHEMBL2062154 | PD-134308)
Affinity DataKi:  7.30nMAssay Description:Compound was tested for binding affinity against rat brain Cholecystokinin type B receptor expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087107(C-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-methyl...)
Affinity DataKi:  7.60nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087090(C-({2-[(Carboxy-phenyl-methyl)-carbamoyl]-3-phenyl...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087116(C-{[3-Biphenyl-4-yl-2-(1-carboxy-2-hydroxy-propylc...)
Affinity DataKi:  10.2nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105261(1-[2-(1-Benzyloxycarbonyl-2-phenyl-ethylcarbamoyl)...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, aminopeptidase N(APN)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087110(1-{[2-(1-Carboxy-ethylcarbamoyl)-3-(4-isopropyl-ph...)
Affinity DataKi:  11.4nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087086(1-{[2-(2-Biphenyl-4-yl-1-carboxy-ethylcarbamoyl)-3...)
Affinity DataKi:  11.7nMAssay Description:Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50087119(C-{[3-Biphenyl-4-yl-2-(1-carboxy-2-hydroxy-ethylca...)
Affinity DataKi:  11.8nMAssay Description:Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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