Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 4.48E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 4.66E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 4.85E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 7.74E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University College Dublin
Curated by ChEMBL
University College Dublin
Curated by ChEMBL
Affinity DataIC50: 8.95E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.30E+4nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.80E+4nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.80E+4nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair