Found 76 with Last Name = 'o''neill' and Initial = 'mt' 
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Plasmodium falciparum PMV assessed as fluorogenic substrate cleavage using DABCYL-RNKRTLAQKQ-E-EDANS as fluorogenic substrate after 120...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetPlasmepsin V(Plasmodium vivax)
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of Plasmodium vivax plasmepsin V by fluorogenic PEXEL cleavage assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 348nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 556nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 569nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 613nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 614nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 622nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 625nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 713nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 772nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 865nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 967nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
The Walter And Eliza Hall Institute Of Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
