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Found 80 with Last Name = 'o''shea' and Initial = 'km'
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196941(CHEMBL246365 | N2-(2-chlorobenzyl)-N4-((3-(aminome...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196932(CHEMBL392642 | N2-(2-(methylthio)benzyl)-N4-((4-(a...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196957(CHEMBL246175 | N2-(2-bromobenzyl)-N4-((4-(aminomet...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196961(CHEMBL246174 | N2-(2-(trifluoromethylthio)benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196936(CHEMBL246386 | N2-(2,5-dichlorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196978(CHEMBL246183 | N2-(2,3-dichlorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196959(CHEMBL396929 | N2-(2-nitrobenzyl)-N4-((4-(aminomet...)
Affinity DataIC50:  11nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196951(CHEMBL247979 | N2-(2-(trifluoromethyl)benzyl)-N4-(...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196987(CHEMBL245912 | N2-(2,3-dimethylbenzyl)-N4-((4-(ami...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196991(CHEMBL245977 | N2-(2-(difluoromethyl)benzyl)-N4-((...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196952(CHEMBL395690 | N2-(2-methoxybenzyl)-N4-((4-(aminom...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196972(CHEMBL248183 | N2-(2-(trifluoromethoxy)benzyl)-N4-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196958(CHEMBL246159 | N2-(2-chlorobenzyl)-N4-(((1s,4s)-4-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196975(CHEMBL245783 | N2-(2,3-difluorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196990(CHEMBL246184 | N2-(2,4-dichlorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  27nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196982(CHEMBL395691 | N2-(2-chlorobenzyl)-N4-(((1r,4r)-4-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196980(CHEMBL247572 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  31nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196948(CHEMBL428751 | N*4*-(4-aminomethyl-cyclohexylmethy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196956(CHEMBL396370 | N2-(2,5-difluorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196954(CHEMBL246177 | N*4*-(4-aminomethyl-cyclohexylmethy...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196973(CHEMBL438669 | N*4*-(4-aminomethyl-cyclohexylmethy...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196935(CHEMBL246182 | N2-(2,6-difluorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  42nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196930(CHEMBL246970 | N2-(2-chlorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196984(CHEMBL246387 | N2-(3-chloro-2-methylbenzyl)-N4-((4...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196985(CHEMBL395689 | N2-(2-fluorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  48nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196937(CHEMBL391610 | N2-(3-fluorophenethyl)-N4-((4-(amin...)
Affinity DataIC50:  54nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196931(CHEMBL246160 | N2-(2-chlorobenzyl)-N4-((4-((dimeth...)
Affinity DataIC50:  54nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196965(CHEMBL396924 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  60nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196968(CHEMBL247377 | N2-(4-fluorophenethyl)-N4-((4-(amin...)
Affinity DataIC50:  77nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196944(CHEMBL245757 | N2-(3-fluorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  83nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196934(CHEMBL437941 | N2-(3-chlorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  85nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196942(CHEMBL391609 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  90nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196943(CHEMBL246161 | N2-(2-chlorobenzyl)-5-nitro-N4-(pip...)
Affinity DataIC50:  90nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196963(CHEMBL247573 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  94nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196974(CHEMBL245982 | N2-(2,4-difluorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196966(CHEMBL246367 | N2-(2-chlorobenzyl)-N4-(7-aminohept...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196977(CHEMBL247177 | N2-(2-fluorophenethyl)-N4-((4-(amin...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196962(CHEMBL391753 | N2-(2-chlorobenzyl)-N4-(4-(aminomet...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196945(CHEMBL246972 | N2-(4-chlorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  170nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196955(CHEMBL247176 | N*4*-(4-aminomethyl-cyclohexylmethy...)
Affinity DataIC50:  180nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196983(CHEMBL391754 | N2-(2-chlorobenzyl)-N4-(3-(aminomet...)
Affinity DataIC50:  200nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196967(CHEMBL245958 | N2-(4-fluorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  210nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196971(CHEMBL395160 | N2-(3-methoxybenzyl)-N4-((4-(aminom...)
Affinity DataIC50:  210nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196933(CHEMBL397397 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  270nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196930(CHEMBL246970 | N2-(2-chlorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  290nMAssay Description:Inhibition of PKCtheta in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196949(CHEMBL394113 | N2-(3,5-dichlorobenzyl)-N4-((4-(ami...)
Affinity DataIC50:  400nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196981(CHEMBL246366 | N2-(2-chlorobenzyl)-N4-(5-aminopent...)
Affinity DataIC50:  450nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196946((R)-N4-((4-(aminomethyl)cyclohexyl)methyl)-N2-(2,3...)
Affinity DataIC50:  460nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196960(CHEMBL247571 | N4-((4-(aminomethyl)cyclohexyl)meth...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PKCtheta by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50196930(CHEMBL246970 | N2-(2-chlorobenzyl)-N4-((4-(aminome...)
Affinity DataIC50:  630nMAssay Description:Inhibition of PKCtheta in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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