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Found 412 with Last Name = 'oates' and Initial = 'b'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity of the compound against specific binding of [125I]-MIP-1 alpha to human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105510(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-m...)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105517(Allyl-[1-((3S,4S)-1-benzyl-4-phenyl-pyrrolidin-3-y...)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339214(CHEMBL1689480)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105503(Allyl-[1-((3S,4S)-1-benzoyl-4-phenyl-pyrrolidin-3-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105521(Allyl-[1-((3S,4S)-1-cyclopentanecarbonyl-4-phenyl-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339209(CHEMBL1689479)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104257(CHEMBL432360 | N-((R)-4-{4-[1-Allyl-3-(4-nitro-ben...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105543(Allyl-{1-[(3S,4S)-1-(2-chloro-benzoyl)-4-phenyl-py...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105555(Allyl-{1-[(3S,4S)-1-(naphthalene-1-carbonyl)-4-phe...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105544(Allyl-[1-((3S,4S)-1-cyclohexanecarbonyl-4-phenyl-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104273(CHEMBL310106 | {1-[(S)-4-(Benzenesulfonyl-methyl-a...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339210(CHEMBL1689481)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104238(CHEMBL421342 | {1-[(S)-4-(Benzenesulfonyl-methyl-a...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104251(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104238(CHEMBL421342 | {1-[(S)-4-(Benzenesulfonyl-methyl-a...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104254(CHEMBL82048 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104249(CHEMBL81252 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104251(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339191(CHEMBL1689460)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106932((1-{3-(3-Chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmet...)
Affinity DataIC50:  2nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105557(CHEMBL93851 | {1-[(3S,4S)-1-(2-Chloro-benzoyl)-4-p...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104235(CHEMBL85086 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104241(CHEMBL311248 | N-Allyl-N-{1-[(R)-4-(benzenesulfony...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105540(CHEMBL430867 | [1-((3S,4S)-1-Cyclopentanecarbonyl-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104275(CHEMBL79622 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104258(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104262(Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104260(CHEMBL79530 | N-{4-[4-(3-Benzyl-1-propyl-ureido)-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104253(CHEMBL311261 | {1-[(S)-4-(Benzenesulfonyl-methyl-a...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104270(CHEMBL81245 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104256(CHEMBL83057 | N-{1-[(R)-4-(Benzenesulfonyl-methyl-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104261(CHEMBL83823 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106929(Allyl-(1-{3-(3-chloro-phenyl)-4-[(R)-4-(1H-indol-3...)
Affinity DataIC50:  3nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339211(CHEMBL1689482)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105500(CHEMBL329140 | Ethyl-{1-[(3S,4S)-1-(naphthalene-1-...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339201(CHEMBL1689470)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339193(CHEMBL1689463)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339193(CHEMBL1689463)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106952(Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-pip...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104247(CHEMBL313216 | {1-[(S)-4-(Benzenesulfonyl-methyl-a...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104264(CHEMBL445836 | N-Methyl-N-{2-phenyl-4-[4-(3-phenyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106931(CHEMBL106907 | Ethyl-(1-{4-[(R)-4-(1H-indol-3-ylme...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104281(CHEMBL84309 | N-{1-[(R)-4-(Benzenesulfonyl-methyl-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096519(Benzoic acid (S)-2-(3,4-dichloro-phenyl)-4-(spiro[...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligand at a concentration of 1000 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104274(CHEMBL81926 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to human CCR5 receptor expressed in Chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105541(CHEMBL329417 | [1-((3S,4S)-1-Cyclohexanecarbonyl-4...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration, binding towards C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligand expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096520(Benzyl (S)-2-(3,4-dichloro-phenyl)-4-(spiro[1-benz...)
Affinity DataIC50:  4nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligand at a concentration of 1000 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106930(Allyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo...)
Affinity DataIC50:  5nMAssay Description:Binding affinity against C-C chemokine receptor type 5 stably expressed in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as the radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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