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maximum 50k data
Found 82 with Last Name = 'ohishi' and Initial = 't'
LigandPNGBDBM25041(N'-[(1E)-{6-cyanoimidazo[1,2-a]pyridin-3-yl}methyl...)
Affinity DataIC50:  0.260nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25037(N'-[(1E)-{6-chloroimidazo[1,2-a]pyridin-3-yl}methy...)
Affinity DataIC50:  0.770nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25052(3-{6-bromoimidazo[1,2-a]pyridin-3-yl}-1-[(2-methyl...)
Affinity DataIC50:  1.80nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  2.5nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25050(3-{6-chloro-2-methylimidazo[1,2-a]pyridin-3-yl}-1-...)
Affinity DataIC50:  2.80nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  2.80nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25030(3-{6-bromo-2-methylimidazo[1,2-a]pyridin-3-yl}-1-[...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25030(3-{6-bromo-2-methylimidazo[1,2-a]pyridin-3-yl}-1-[...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
LigandPNGBDBM25038(N'-[(1E)-{6-fluoroimidazo[1,2-a]pyridin-3-yl}methy...)
Affinity DataIC50:  5.30nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25040(N,2-dimethyl-N'-[(1E)-{6-methylimidazo[1,2-a]pyrid...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25039(N,2-dimethyl-5-nitro-N'-[(1E)-[6-(trifluoromethyl)...)
Affinity DataIC50:  14nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207163(4-morpholin-4-yl-2-[3-(2-morpholin-4-yl-ethoxy)-ph...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  16nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25032(N'-[(1E)-1-{6-bromoimidazo[1,2-a]pyridin-3-yl}ethy...)
Affinity DataIC50:  17nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25057(imidazo[1,2-a]pyridine derivative, 14b | {2-[(4-{6...)
Affinity DataIC50:  20nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25033(N'-[(1E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methyl...)
Affinity DataIC50:  21nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207172(CHEMBL534951 | [3-(4-morpholin-4-yl-pyrido[3',2':4...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207169(4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...)
Affinity DataIC50:  26nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25055(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  31nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207173(4-morpholin-4-yl-2-[3-(2-thiomorpholin-4-yl-ethoxy...)
Affinity DataIC50:  79nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25035(N'-[(1E)-1-{6-bromoimidazo[1,2-a]pyridin-3-yl}ethy...)
Affinity DataIC50:  81nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25054(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  82nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207170(2-(3-methoxy-phenyl)-4-morpholin-4-yl-pyrido[3',2'...)
Affinity DataIC50:  100nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25053(3-{6-chloroimidazo[1,2-a]pyridin-3-yl}-1-[(2-methy...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50207167(3-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...)
Affinity DataIC50:  140nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207165(4-morpholin-4-yl-2-phenyl-pyrido[3',2':4,5]furo[3,...)
Affinity DataIC50:  160nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25034(N'-[(1E)-1-{6-bromo-2-methylimidazo[1,2-a]pyridin-...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207175(4-morpholin-4-yl-2-[3-(2-piperidin-1-yl-ethoxy)-ph...)
Affinity DataIC50:  170nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  220nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  230nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  250nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25049(3-{6-chloro-2-methylimidazo[1,2-a]pyridin-3-yl}-1-...)
Affinity DataIC50:  280nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  340nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25042(ethyl 3-[(1E)-{[methyl(2-methyl-5-nitrobenzene)sul...)
Affinity DataIC50:  340nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  340nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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