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Found 217 with Last Name = 'oliaro-bosso' and Initial = 's'
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255431(4-(trifluoromethyl)phenyl 4-(5-(allyl(methyl)amino...)
Affinity DataIC50:  50nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593724(CHEMBL5194388)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50255432(CHEMBL516921 | N-allyl-4-(3-(4-bromophenyl)benzo[d...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255474(4-(5-(3-(4-bromophenyl)benzo[d]isothiazol-6-yl)pen...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  100nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255531(4-chlorophenyl 4-(5-(ethyl(2-hydroxyethyl)amino)pe...)
Affinity DataIC50:  100nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255532(CHEMBL481199 | N-(4-(5-(allyl(methyl)amino)pentyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593730(CHEMBL5172658)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50509767(CHEMBL4513510)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 assessed as reduction in NADPH-dependent 9,10-phenanthrenequinone convers...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255433(4-(4-(3-(4-bromophenyl)benzo[d]isothiazol-6-yloxy)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255431(4-(trifluoromethyl)phenyl 4-(5-(allyl(methyl)amino...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128062((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
Affinity DataIC50:  180nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593732(CHEMBL5174744)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50462392(CHEMBL4248154)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50433360(CHEMBL2375380)
Affinity DataIC50:  200nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8[pSM60.21] using [14C]-(3S)-2,3-oxidosqualene as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593726(CHEMBL5204156)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  210nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128056((E)-N-allyl-4-(3-(4-bromophenyl)benzofuran-6-yloxy...)
Affinity DataIC50:  210nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593727(CHEMBL5170149)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255475(2-((5-(3-(4-bromophenyl)benzo[d]isothiazol-6-yl)pe...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50128070((4''-{[ALLYL(METHYL)AMINO]METHYL}-1,1''-BIPHENYL-4...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50128070((4''-{[ALLYL(METHYL)AMINO]METHYL}-1,1''-BIPHENYL-4...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593728(CHEMBL5170401)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50462395(CHEMBL4238437)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50255432(CHEMBL516921 | N-allyl-4-(3-(4-bromophenyl)benzo[d...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50128062((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593729(CHEMBL5175151)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLanosterol synthase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50128062((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255430(CHEMBL473035 | N-(4-(5-(ethyl(2-hydroxyethyl)amino...)
Affinity DataIC50:  270nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128052(Allyl-{6-[4-(6-bromo-benzo[d]isothiazol-3-yl)-phen...)
Affinity DataIC50:  280nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128058(ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6...)
Affinity DataIC50:  290nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255476(2-((3-(3-(4-bromophenyl)benzo[d]isothiazol-6-yl)pr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50509974(CHEMBL4434843)
Affinity DataIC50:  300nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human AKR1C3 His5Gln mutant expressed in Escherichia coli BL21 (DE) Codon Plus RP cells assessed as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50433362(CHEMBL2377451)
Affinity DataIC50:  300nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8[pSM60.21] using [14C]-(3S)-2,3-oxidosqualene as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50255532(CHEMBL481199 | N-(4-(5-(allyl(methyl)amino)pentyl)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593725(CHEMBL5206583)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50462394(CHEMBL4249650)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)
Affinity DataIC50:  310nMAssay Description:Inhibition of AKR1C3 (unknown origin) using S-tetralol as substrate in presence of NADP+ by fluorimteryMore data for this Ligand-Target Pair
TargetLanosterol synthase ERG7(Saccharomyces cerevisiae)
Università

Curated by ChEMBL
LigandPNGBDBM50128070((4''-{[ALLYL(METHYL)AMINO]METHYL}-1,1''-BIPHENYL-4...)
Affinity DataIC50:  320nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCycloartenol synthase(Arabidopsis thaliana)
Università

Curated by ChEMBL
LigandPNGBDBM50255602(CHEMBL520926 | N-(4-(4-(1-(diethylamino)cyclopropy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Pneumocystis carinii)
Universit£

Curated by ChEMBL
LigandPNGBDBM50195963((4E,8E)-N,N,4,8-tetramethyl-10-(3-phenylpropoxy)de...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Pneumocystis carinii oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Pneumocystis carinii)
Universit£

Curated by ChEMBL
LigandPNGBDBM50195962((4E,8E)-10-(hexyloxy)-N,N,4,8-tetramethyldeca-4,8-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of Pneumocystis carinii oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50593722(CHEMBL5191752)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin

Curated by ChEMBL
LigandPNGBDBM50462391(CHEMBL4238142)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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