TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 181nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 361nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 363nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 431nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 516nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 869nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 879nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Pyk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair