TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.313nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.534nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Inhibition of rat prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-JNJ962 from BACE1 (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant by scintillation counting a...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of rat prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]DTG from sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of [3H]-Iloprost binding to human prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 57nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Fujisawa Pharmaceutical
Curated by ChEMBL
Fujisawa Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
Affinity DataKi: 114nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair
Affinity DataKi: 115nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 119nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair