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Found 260 with Last Name = 'oppenheimer' and Initial = 's'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28030(2-aminopyridine analogue, 9 | N-{4-[(2-amino-3-chl...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28028(2-aminopyridine analogue, 7 | N-{4-[(2-amino-3-eth...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24440(2-pyridone analogue, 2 | JMC521251 Compound 1 | N-...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28033(2-aminopyridine analogue, 12 | N-{4-[(2-amino-3-ch...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28026(2-aminopyridine analogue, 5 | N-(4-{[2-amino-3-(3-...)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28032(2-aminopyridine analogue, 11 | N-{4-[(2-amino-3-ch...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28027(2-aminopyridine analogue, 6 | N-(4-{[2-amino-3-(hy...)
Affinity DataIC50:  3.40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28029(2-aminopyridine analogue, 8 | N-(4-{[2-amino-3-(pr...)
Affinity DataIC50:  3.40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28025(2-aminopyridine analogue, 4 | N-(4-{[2-amino-3-(3-...)
Affinity DataIC50:  3.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28031(BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...)
Affinity DataIC50:  3.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333374(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloropheny...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333375(5-((4-aminopiperidin-1-yl)methyl)-N-(3-bromophenyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28023(N-{4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}-1-...)
Affinity DataIC50:  4.5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333376(5-((4-aminopiperidin-1-yl)methyl)-N-m-tolylpyrrolo...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28024(2-aminopyridine analogue, 3 | N-[4-({2-amino-3-[(4...)
Affinity DataIC50:  5.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333377(5-((4-aminopiperidin-1-yl)methyl)-N-p-tolylpyrrolo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333378(5-((4-aminopiperidin-1-yl)methyl)-N-(3-fluoropheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333375(5-((4-aminopiperidin-1-yl)methyl)-N-(3-bromophenyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333372(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-fl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333379(5-((4-aminopiperidin-1-yl)methyl)-N-(3-ethynylphen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333374(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloropheny...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333380(5-((4-aminopiperidin-1-yl)methyl)-N-phenylpyrrolo[...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333379(5-((4-aminopiperidin-1-yl)methyl)-N-(3-ethynylphen...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333372(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-fl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217195(5-((4-aminopiperidin-1-yl)methyl)-N-(1-((5-methylp...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50208409((S)-1-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299488(CHEMBL565467 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299487(CHEMBL565714 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217188(CHEMBL248322 | [5-(4-amino-piperidin-1-ylmethyl)-p...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50204120(2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299489(CHEMBL567197 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217195(5-((4-aminopiperidin-1-yl)methyl)-N-(1-((5-methylp...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant EGFR expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299489(CHEMBL567197 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333382(5-((4-aminopiperidin-1-yl)methyl)-N-o-tolylpyrrolo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333376(5-((4-aminopiperidin-1-yl)methyl)-N-m-tolylpyrrolo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333381((S)-N-(3-ethynylphenyl)-5-((morpholin-2-ylmethoxy)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299487(CHEMBL565714 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299490(CHEMBL567873 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217206(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(p...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333373(CHEMBL1645462 | [4-[[1-(3-fluorophenyl)methyl]-1H-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299491(CHEMBL583403 | [4-[[1-(3-fluorophenyl)methyl]-1H-i...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217191(CHEMBL248108 | N-(1-(3-fluorobenzyl)-1H-indazol-5-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217191(CHEMBL248108 | N-(1-(3-fluorobenzyl)-1H-indazol-5-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333373(CHEMBL1645462 | [4-[[1-(3-fluorophenyl)methyl]-1H-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299491(CHEMBL583403 | [4-[[1-(3-fluorophenyl)methyl]-1H-i...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299488(CHEMBL565467 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50299492(CHEMBL583218 | {4-(1-Benzyl-1H-indazol-5-ylamino)-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50217186(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(p...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50208409((S)-1-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50208401(5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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