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Found 41 with Last Name = 'osifo' and Initial = 'ik'
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286304((R)-3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methy...)
Affinity DataKi:  15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCaspase-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50176519((S)-3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methy...)
Affinity DataKi:  15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286446(CHEMBL341222 | {(S)-1-[(S)-1-(4-Hydroxy-benzyl)-2-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286452(CHEMBL340020 | {(S)-1-[(S)-1-(4-Hydroxy-benzyl)-2-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286449(CHEMBL338859 | {(S)-1-[(S)-1-(4-Methoxy-benzyl)-2-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50137397(CHEMBL341014 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50014577(CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286453(CHEMBL419423 | {(S)-1-[(S)-1-(4-Hydroxy-benzyl)-2-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286444(CHEMBL339000 | [(S)-1-((S)-1-Formyl-3-phenyl-propy...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286445(CHEMBL127613 | [((S)-1-Benzyl-2-oxo-ethylcarbamoyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286454(CHEMBL129657 | [(S)-1-((S)-1-Formyl-2-naphthalen-1...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286455(CHEMBL128775 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286443(CHEMBL128776 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286456(CHEMBL129458 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213272(CHEBI:6426 | Leupeptin)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286450(CHEMBL128135 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286432(1-(4-Hydroxy-2-methyl-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286451(CHEMBL129823 | [1-((S)-1-Benzyl-2-oxo-ethylcarbamo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286434(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286434(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286442(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyrazol-1-yl...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286447(CHEMBL2370670 | [1-(2-Formyl-pyrrolidine-1-carbony...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286448(CHEMBL127663 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Calpain 1 by [3H]-acetyl-casein assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286430(1-(4-Hydroxy-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihy...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286429(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridazin-3-...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286440(1-(2-Chloro-4-hydroxy-phenyl)-7-furan-3-yl-4-oxo-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286426(1-(2-Chloro-4-hydroxy-phenyl)-7-(3-chloro-pyridin-...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286436(1-(3-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286437(1-(3-Fluoro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286435(1-(3,4-Dihydroxy-phenyl)-4-oxo-7-pyridin-4-yl-1,4-...)
Affinity DataIC50:  7.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286433(1-(2-Fluoro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  7.00E+3nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286439(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-3-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286438(1-(4-Hydroxy-2-trifluoromethyl-phenyl)-4-oxo-7-pyr...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286431(1-(4-Hydroxy-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihy...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetProcathepsin L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286434(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibitory activity against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286434(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-4-yl...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286427(1-(2-Chloro-4-hydroxy-phenyl)-7-(2-fluoro-pyridin-...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286428(1-(2-Chloro-4-hydroxy-phenyl)-4-oxo-7-pyridin-2-yl...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286430(1-(4-Hydroxy-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihy...)
Affinity DataIC50:  3.20E+4nMAssay Description:In vitro inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProcathepsin L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286430(1-(4-Hydroxy-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihy...)
Affinity DataIC50:  3.70E+4nMAssay Description:In vitro inhibitory activity against cathepsin LMore data for this Ligand-Target Pair
In DepthDetails Article