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Found 218 with Last Name = 'owen' and Initial = 'cp'
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  0.0650nMAssay Description:Inhibitory concentration required to inhibit the enzyme estrone sulfatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  0.0650nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  8nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50:  14nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50:  34nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50078543(CHEMBL44459 | Sulfamic acid 4-(2-tetradecanoylamin...)
Affinity DataIC50:  56nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296974(4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...)
Affinity DataIC50:  65.1nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50:  70nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50:  70nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296973(4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...)
Affinity DataIC50:  70.4nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296970(4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...)
Affinity DataIC50:  85nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296972(4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...)
Affinity DataIC50:  98.7nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for its inhibitory activity against estrone sulfatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296975(4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...)
Affinity DataIC50:  101nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50:  110nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188093(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)
Affinity DataIC50:  130nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50:  130nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50:  160nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  164nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50139114(4-Sulfamoyloxy-benzoic acid cyclooctyl ester | CHE...)
Affinity DataIC50:  170nMAssay Description:Inhibition of estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  206nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  210nMAssay Description:Compound was evaluated for its inhibitory activity against estrone sulfatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50:  210nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50:  230nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50:  291nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50191795(CHEMBL386256 | N-3-(4-bromophenyl)propyl imidazole)
Affinity DataIC50:  330nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50051829(4-methyl-2-oxo-2H-chromen-7-yl sulfamate | CHEMBL1...)
Affinity DataIC50:  380nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of estrone sulfatase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of estrone sulfatase (ES)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50139113(4-Sulfamoyloxy-benzoic acid cycloheptyl ester | CH...)
Affinity DataIC50:  500nMAssay Description:Inhibition of estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of estrone sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50191792(1-(3-(4-chlorophenyl)propyl)-1H-imidazole | CHEMBL...)
Affinity DataIC50:  550nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  730nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50:  880nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Kingston University

Curated by ChEMBL
LigandPNGBDBM50078542(CHEMBL26036 | Sulfamic acid 5,6,7,8-tetrahydro-nap...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for the inhibitory activity against Estrone SulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50008733(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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