Compile Data Set for Download or QSAR
maximum 50k data
Found 145 with Last Name = 'paine' and Initial = 'sw'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344999(2-(2'-chloro-4'-(N-methylmethylsulfonamido)-5-(tri...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344993(2-(2'-chloro-4'-(methylsulfonyl)-5-(trifluoromethy...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344995(2-(5'-cyano-2'-methyl-5-(trifluoromethyl)biphenyl-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344996(2-(5'-cyano-2'-fluoro-5-(trifluoromethyl)biphenyl-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344992(2-(2'-chloro-4'-(ethylsulfonyl)-5-(trifluoromethyl...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339747((S)-2-(2-((4-(2-(4-fluorophenyl)acetyl)-3-methylpi...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423388(CHEMBL251024)
Affinity DataIC50:  0.320nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as ADP-induced human platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344998(2-(2'-methyl-4'-(N-methylmethylsulfonamido)-5-(tri...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50026419(CHEMBL1778628)
Affinity DataIC50: <0.400nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423387(CHEMBL437204)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as ADP-induced human platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339748(CHEMBL1689128 | [4-Chloro-2-[[(3S)-4-[(4-chlorophe...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339749((S)-2-(2-((4-(benzylsulfonyl)-3-methylpiperazin-1-...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344974((R)-2-(3'-cyano-5-(trifluoromethyl)biphenyl-2-ylox...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344988(2-(2',5-dichloro-4'-(methylsulfonyl)biphenyl-2-ylo...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344975((2R)-2-(2'-chloro-4'-(ethylsulfonyl)-5-(trifluorom...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339750((S)-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)pip...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345003(2-(4'-(N-methylmethylsulfonamido)-5-(trifluorometh...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344991(2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339751((S)-2-(4-chloro-2-((4-(2-(4-fluorophenyl)acetyl)-3...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344991(2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to mouse CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339753((S)-2-(4-chloro-2-(((S)-4-(2-(4-chlorophenyl)acety...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339752((S)-2-(4-chloro-2-((4-(phenylsulfonyl)-3-propylpip...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Rattus norvegicus)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344991(2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity to rat CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345007(2-(4'-(N,N-diethylsulfamoyl)-5-(trifluoromethyl)bi...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344984(2-(2',5-dichloro-4'-(ethylsulfonyl)biphenyl-2-ylox...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344982((2R)-2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluorom...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344994(2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345001((5-Trifluoromethyl-[1,1':2',1'']terphenyl-2-yloxy)...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344997(2-(2'-chloro-5-fluoro-4'-(N-methylmethylsulfonamid...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339754(CHEMBL1689135 | [4-Chloro-2-({(3S)-4-[(4-chlorophe...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188311(2-(3-(8-chloroquinolin-4-yl)-2,5-dimethyl-1H-indol...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344978(3-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188301(2-(2,5-dimethyl-3-(8-methylquinolin-4-yl)-1H-indol...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339755((S)-2-(4-chloro-2-((3-methyl-4-(2-phenylacetyl)pip...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344985(2-(5-chloro-4'-(ethylsulfonyl)-2'-methylbiphenyl-2...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339750((S)-2-(4-chloro-2-((3-methyl-4-(phenylsulfonyl)pip...)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339756((S)-2-(4-chloro-2-((3-ethyl-4-(phenylsulfonyl)pipe...)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188300(2-(2,5-dimethyl-3-(7-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339757((S)-2-(4-chloro-2-((4-(2-(2-chlorophenyl)acetyl)-3...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339758(2-(2-((4-(benzylsulfonyl)piperazin-1-yl)methyl)-4-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188305(2-(2,5-dimethyl-3-(8-(trifluoromethyl)quinolin-4-y...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339759((S)-2-(4-chloro-2-((4-(2-(3-chlorophenyl)acetyl)-3...)
Affinity DataIC50:  6.80nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188309(2-(3-(8-fluoroquinolin-4-yl)-2,5-dimethyl-1H-indol...)
Affinity DataIC50:  7.10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344986(2-(5-chloro-4'-(ethylsulfonyl)-2'-fluorobiphenyl-2...)
Affinity DataIC50:  7.90nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188307(2-(3-(7-chloroquinolin-4-yl)-2,5-dimethyl-1H-indol...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345008(2-(4'-(ethylthio)-5-(trifluoromethyl)biphenyl-2-yl...)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339748(CHEMBL1689128 | [4-Chloro-2-[[(3S)-4-[(4-chlorophe...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339751((S)-2-(4-chloro-2-((4-(2-(4-fluorophenyl)acetyl)-3...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50344994(2-(5-chloro-3'-cyanobiphenyl-2-yloxy)acetic acid |...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-induced calcium flux in presence of 1% bovine serum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339760(2-(4-chloro-2-((4-(4-fluorophenylsulfonyl)piperazi...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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