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Found 157 with Last Name = 'papoulis' and Initial = 'at'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  3nMAssay Description:Compound was tested for inhibition activity against rat liver lipophilic Dihydrofolate reductase (DHFR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(5-(3,5-Diethoxy-4-pyrrol-1-yl-benzyl)-pyrimidine-2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for inhibition activity against toxoplasma gondii (T. gondii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(5-(3,5-Diethoxy-4-pyrrol-1-yl-benzyl)-pyrimidine-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of T. gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18506(6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082920(6-Carbazol-9-ylmethyl-pteridine-2,4-diamine | CHEM...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074735(6-(3-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  14nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074724(6-(2-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  14nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inhibition activity against rat liver lipophilic Dihydrofolate reductase (DHFR).More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(5-(4-Bromo-3,5-dimethoxy-benzyl)-pyrimidine-2,4-di...)
Affinity DataIC50:  15nMAssay Description:Inhibition of rat liver Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  15nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  17nMAssay Description:Compound was tested for inhibition activity against toxoplasma gondii (T. gondii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(5-(4-Bromo-3,5-dimethoxy-benzyl)-pyrimidine-2,4-di...)
Affinity DataIC50:  17nMAssay Description:Inhibition of T. gondii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  17nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...)
Affinity DataIC50:  18nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  21nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  21nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074727(6-(2-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  23nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074719(6-(3,4-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  23nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074721(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-qui...)
Affinity DataIC50:  24nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082922(6-Phenothiazin-10-ylmethyl-pteridine-2,4-diamine |...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  31nMAssay Description:Compound was tested for inhibition activity against pneumocystis carinii (P. carinii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027970(5-(4-Bromo-3,5-dimethoxy-benzyl)-pyrimidine-2,4-di...)
Affinity DataIC50:  31nMAssay Description:Inhibition of P. carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  31nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074723(6-Benzyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamin...)
Affinity DataIC50:  32nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  34nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074722(6-(3-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  36nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074721(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-qui...)
Affinity DataIC50:  38nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074732(6-(Tetrahydro-furan-2-ylmethyl)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  40nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029763(5-(3,5-Diethoxy-4-pyrrol-1-yl-benzyl)-pyrimidine-2...)
Affinity DataIC50:  42nMAssay Description:Inhibition of P. carinii Dihydrofolate ReductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50:  42nMAssay Description:Compound was tested for inhibition activity against pneumocystis carinii (P. carinii) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18506(6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074728(6-(thiophen-3-ylmethyl)-5,6,7,8-tetrahydroquinazol...)
Affinity DataIC50:  49nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074734(6-(4-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  50nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)
Affinity DataIC50:  54nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082920(6-Carbazol-9-ylmethyl-pteridine-2,4-diamine | CHEM...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  57nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074737(6-Thiophen-2-ylmethyl-5,6,7,8-tetrahydro-quinazoli...)
Affinity DataIC50:  62nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074719(6-(3,4-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  63nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...)
Affinity DataIC50:  65nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  73nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074734(6-(4-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  77nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074735(6-(3-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  79nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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