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Found 167 with Last Name = 'park' and Initial = 'jm'
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50451005(CHEMBL290376 | DuP-714)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of Coagulation factor IIMore data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084682(1-[3-(4-Carbamimidoyl-phenyl)-2-(2-methyl-1,2,3,4-...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094092(CHEMBL336661 | N-(3-Bromo-2'-sulfamoyl-biphenyl-4-...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289591(2'-Diethylsulfamoyl-3-methyl-biphenyl-4-carboxylic...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289587(3-Methyl-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  0.420nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289575(3-Methyl-2'-trifluoromethyl-biphenyl-4-carboxylic ...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094100(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(3-iodo-2'-sul...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289591(2'-Diethylsulfamoyl-3-methyl-biphenyl-4-carboxylic...)
Affinity DataKi:  0.620nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289582(3-Methyl-2'-methylsulfonylcarbamate-biphenyl-4-car...)
Affinity DataKi:  0.640nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094096(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(3-chloro-2'-s...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084682(1-[3-(4-Carbamimidoyl-phenyl)-2-(2-methyl-1,2,3,4-...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094096(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(3-chloro-2'-s...)
Affinity DataKi:  0.790nMAssay Description:Binding affinity against Coagulation factor X from rabbit purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094092(CHEMBL336661 | N-(3-Bromo-2'-sulfamoyl-biphenyl-4-...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against Coagulation factor X from rabbit purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094115(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-[5-(2-sulfamoy...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094115(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-[5-(2-sulfamoy...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094115(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-[5-(2-sulfamoy...)
Affinity DataKi:  0.930nMAssay Description:Binding affinity against Coagulation factor X from rabbit purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289576(Biphenyl-4-carboxylic acid [(R)-4-guanidino-1-((2S...)
Affinity DataKi:  0.940nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289582(3-Methyl-2'-methylsulfonylcarbamate-biphenyl-4-car...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289598(3-Fluoro-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289588(3-Amino-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289596(CHEMBL264370 | N-[(1S)-4-{[(Z)-amino(imino)methyl]...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12775(2-(5-carbamimidoyl-1H-indol-3-yl)-N-[4-(2-sulfamoy...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094102(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(3-methyl-2'-s...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094114(2-(6-Carbamimidoyl-benzoimidazol-1-yl)-N-(2'-sulfa...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289575(3-Methyl-2'-trifluoromethyl-biphenyl-4-carboxylic ...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094094(2-(6-Carbamimidoyl-indazol-1-yl)-N-[5-(2-sulfamoyl...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094097(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(3-fluoro-2'-s...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094091(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(2'-methylsulf...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289579(3'-Methanesulfonylamino-biphenyl-3-carboxylic acid...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289579(3'-Methanesulfonylamino-biphenyl-3-carboxylic acid...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094113(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(2'-ethylsulfa...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289587(3-Methyl-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289584(3-Nitro-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289595(2-Amino-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289581(2-Nitro-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289581(2-Nitro-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289588(3-Amino-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289595(2-Amino-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12775(2-(5-carbamimidoyl-1H-indol-3-yl)-N-[4-(2-sulfamoy...)
Affinity DataKi:  6nMAssay Description:Binding affinity against fXa from rabbit purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072445(CHEMBL139063 | CHEMBL279628 | [3-(3-Carbamimidoyl-...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289594(2-Biphenyl-4-yl-N-[(R)-4-guanidino-1-((2S,6R)-2,9,...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094093(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(2'-dimethylsu...)
Affinity DataKi:  7nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076548(1-[2-(4-Benzyl-piperidin-1-yl)-2-oxo-ethyl]-3-(2-h...)
Affinity DataKi:  7nMAssay Description:Inhibition of Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50076545(CHEMBL422722 | {1-[2-(4-Benzyl-piperidin-1-yl)-2-o...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289589(Biphenyl-3-carboxylic acid [(R)-4-guanidino-1-((2S...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50094104(2-(5-Carbamimidoyl-1H-indol-3-yl)-N-(2'-propylsulf...)
Affinity DataKi:  8nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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