Compile Data Set for Download or QSAR
maximum 50k data
Found 134 with Last Name = 'parveen' and Initial = 's'
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178811(CHEMBL199020 | N-(3-aminopropyl)-4-tert-butyl-N,N-...)
Affinity DataKi:  150nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178803(3,4-dichloro-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  180nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178803(3,4-dichloro-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  440nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178809(4-tert-butyl-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  570nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178807(3,4-dichloro-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  1.69E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178802(4-tert-butyl-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  2.67E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178805(CHEMBL436292 | N-benzhydryl-3-(5-chloro-2-(phenylt...)
Affinity DataKi:  5.30E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178802(4-tert-butyl-N-(3-(5-chloro-2-(phenylthio)phenylam...)
Affinity DataKi:  6.50E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178804(4-(benzyloxy)-N-(3-(5-chloro-2-(phenylthio)phenyla...)
Affinity DataKi:  6.60E+3nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178810(CHEMBL371088 | N-(5-chloro-2-(phenylthio)phenyl)bu...)
Affinity DataKi:  1.13E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178814(CHEMBL199067 | N-(3-(5-chloro-2-(phenylthio)phenyl...)
Affinity DataKi:  1.42E+4nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178808(CHEMBL372379 | N-(5-chloro-2-(phenylthio)phenyl)pr...)
Affinity DataKi:  2.00E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178801(CHEMBL198590 | N-(5-chloro-2-(phenylthio)phenyl)be...)
Affinity DataKi:  2.45E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178812(CHEMBL197131 | N-(5-chloro-2-(phenylthio)phenyl)-2...)
Affinity DataKi:  2.46E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178806(CHEMBL370195 | N-(5-chloro-2-(phenylthio)phenyl)-4...)
Affinity DataKi:  4.28E+4nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178809(4-tert-butyl-N-(3-(2-chloro-10H-phenothiazin-10-yl...)
Affinity DataKi:  6.60E+4nMAssay Description:Linear competitive inhibition of trypanothione reductase from Trypanosoma cruzi using (ZCG.dmapa)2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50178813(2-amino-4-chloro-phenyl phenyl sulfide | CHEMBL197...)
Affinity DataKi:  1.50E+5nMAssay Description:Mixed inhibition of trypanothione reductase from Trypanosoma cruzi using TSST substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132447(5-[5-Methoxy-3-(2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132443(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132434(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132436(3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindolin...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132433(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132457(3-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132445(3-[1-(5-Methoxy-1H-indol-3-yl)-meth-(Z)-ylidene]-2...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498187(CHEMBL3409347)
Affinity DataIC50:  32nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132437(3-((1-(3-hydroxypropyl)-5-methoxy-1H-indol-3-yl)me...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of electric eel AChE by modified Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498162(CHEMBL3409362)
Affinity DataIC50:  56nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132441(3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498156(CHEMBL3409344)
Affinity DataIC50:  63nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498169(CHEMBL3409348)
Affinity DataIC50:  69nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  84nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498159(CHEMBL3409349)
Affinity DataIC50:  91nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498185(CHEMBL3409345)
Affinity DataIC50:  95nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132448(2-[3-(5-Methoxy-1-methyl-1H-indol-3-ylmethylene)-2...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132456(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Wistar rat eye lens aldose reductase-2 using D-L glyceraldehyde as substrate assessed as oxidation of NADPH preincubated for 10 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132453(3-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-d...)
Affinity DataIC50:  128nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132449(3-((1-(4-morpholino-4-oxobutyl)-1H-indol-3-yl)meth...)
Affinity DataIC50:  133nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498181(CHEMBL3409346)
Affinity DataIC50:  139nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50497114(CHEMBL3261531)
Affinity DataIC50:  143nMAssay Description:Inhibition of Wistar rat eye lens aldose reductase-2 using D-L glyceraldehyde as substrate assessed as oxidation of NADPH preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50497114(CHEMBL3261531)
Affinity DataIC50:  143nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132451(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-N-...)
Affinity DataIC50:  145nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498186(CHEMBL3409367)
Affinity DataIC50:  153nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498189(CHEMBL3409363)
Affinity DataIC50:  158nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498177(CHEMBL3409366)
Affinity DataIC50:  182nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498158(CHEMBL3409357)
Affinity DataIC50:  191nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132452(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  204nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Birla Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50498166(CHEMBL3409353)
Affinity DataIC50:  238nMAssay Description:Inhibition of Wistar rat lenses ALR2 using D,L-glyceraldehyde as substrate preincubated for 10 mins before substrate addition measured after 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 134 total ) | Next | Last >>
Jump to: