Affinity DataIC50: 1nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair