Compile Data Set for Download or QSAR
maximum 50k data
Found 560 with Last Name = 'peat' and Initial = 'aj'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199266(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-2-na...)
Affinity DataIC50:  0.390nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199205(6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-6-...)
Affinity DataIC50:  0.740nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199251(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-7,8-...)
Affinity DataIC50:  0.75nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199249(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-7,8...)
Affinity DataIC50:  0.870nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199202(6-(4-chlorophenyl)-3-[2-(1-piperidinylmethyl)-6-qu...)
Affinity DataIC50:  0.890nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199254(6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-1-b...)
Affinity DataIC50:  0.910nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422940(CHEMBL213008)
Affinity DataIC50:  1nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199219(6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-6-q...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199248(6-(4-methylphenyl)-3-[2-(pyrrolidin-1-ylmethyl)-1-...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199258(6-(4-chlorophenyl)-3-[1-methyl-2-(pyrrolidin-1-ylm...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199256(6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-5,...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199260(6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-1-...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422936(CHEMBL212657)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199253(6-(4-chlorophenyl)-3-[6-(1-pyrrolidinylmethyl)-5,6...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199229(6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperidinyl)m...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199265(6-(4-chlorophenyl)-3-(2-{[(2R)-2-(methoxymethyl)py...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199223(6-(4-chlorophenyl)-3-[2-({4-[2-(1-pyrrolidinyl)eth...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422927(CHEMBL441368)
Affinity DataIC50:  1.60nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219326(PYRAZOLOPYRIMIDINE 1)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of glycogen synthase kinase-3 (GSK3-beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199214(6-(4-chlorophenyl)-3-[2-(1H-imidazol-1-ylmethyl)-6...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422930(CHEMBL214276)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199252(6-(4-chlorophenyl)-3-[2-(piperidin-1-ylmethyl)-1-b...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199206(6-(4-chlorophenyl)-3-[2-(1-pyrrolidinylmethyl)-3,4...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219327(GW811168X | PYRAZOLOPYRIMIDINE 2)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of glycogen synthase kinase-3 (GSK3-beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422924(CHEMBL214416)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199261(6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxypyrrolidin...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8688((1E)-1-[(4-methanesulfonylphenyl)methylidene]-2-[1...)
Affinity DataIC50:  2.51nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8686(4-[(1E)-{2-[1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  2.51nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199262(6-(4-chlorophenyl)-3-{6-[(dimethylamino)methyl]-7,...)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27747((2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmet...)
Affinity DataIC50:  3nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27730((2S,3R)-3-(tert-butoxy)-2-{[4-(4-methoxyphenyl)-2-...)
Affinity DataIC50:  3nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199257(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-5,6,...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199236(6-(4-chlorophenyl)-3-{2-[(4-methyl-1-piperazinyl)m...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199240(6-(4-chlorophenyl)-3-(2-{[4-(4-fluorophenyl)-1-pip...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8674(4-{4-[(2E)-2-(pyridin-4-ylmethylidene)hydrazin-1-y...)
Affinity DataIC50:  3.16nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199228(6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-3,...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199204(6-(4-chlorophenyl)-3-{(2R)-2-[(dimethylamino)methy...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422926(CHEMBL215565)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199203(6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxy-1-pyrroli...)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199212(6-(4-chlorophenyl)-3-[2-(hydroxymethyl)-6-quinolin...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199217(6-(4-chlorophenyl)-3-{2-[(4-methyl-1-piperazinyl)m...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199215(6-(4-chlorophenyl)-3-{2-[(4-phenyl-1-piperazinyl)m...)
Affinity DataIC50:  3.80nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8687((1E)-1-[(3-methanesulfonylphenyl)methylidene]-2-[1...)
Affinity DataIC50:  3.98nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8695(ethyl({4-[(1E)-{2-[1-(3-methoxyphenyl)-1H-pyrazolo...)
Affinity DataIC50:  3.98nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27745((2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-pr...)
Affinity DataIC50:  4nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50219340(CHEMBL65944)
Affinity DataIC50:  4nMAssay Description:Inhibition of glycogen synthase kinase-3 (GSK3-beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27746((2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-pr...)
Affinity DataIC50:  4nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27743((2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmet...)
Affinity DataIC50:  4nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199216(6-(4-chlorophenyl)-3-[2-(4-morpholinylmethyl)-6-qu...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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