Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.99nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.05nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.32nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.33nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.78nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.12nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9.45nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9.48nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.53nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10.3nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of topoisomerase I activity was determined in vitro by using the cleavable complex assay(calf thymus)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11.1nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11.5nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12.7nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13.2nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 14.1nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of topoisomerase I activity was determined in vitro by using the cleavable complex assay(calf thymus)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17.2nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome
Curated by ChEMBL
Glaxo Wellcome
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19.8nMAssay Description:Binding affinity to cyclophilin B by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair