TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: 55nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells .More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells .More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Putrescine aminopropyltransferase (PAPT) in rat liver.More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.19E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells .More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells .More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 3.75E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 3.96E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+4nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 9.32E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 9.45E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair