Compile Data Set for Download or QSAR
maximum 50k data
Found 360 with Last Name = 'pei' and Initial = 'h'
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  3nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583431(CHEMBL5075663)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271976(LY 2584702 | LY-2584702 | LY2584702)
Affinity DataIC50:  4nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate incubate for 15 mins by LANCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583433(CHEMBL5078528)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583442(CHEMBL5077096)
Affinity DataIC50:  6nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583445(CHEMBL5077973)
Affinity DataIC50:  6nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human YES using biotinyl-beta Abeta-Abeta AYQAEENTYDEYEN as substrate incubate for 30 mins by LANCE assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583441(CHEMBL5082590)
Affinity DataIC50:  7nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583433(CHEMBL5078528)
Affinity DataIC50:  8nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512005(CHEMBL4440181)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583448(CHEMBL5091163)
Affinity DataIC50:  9nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50572395(CHEMBL4864387)
Affinity DataIC50:  9nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583438(CHEMBL5091093)
Affinity DataIC50:  9nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583448(CHEMBL5091163)
Affinity DataIC50:  9nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of ErBB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583427(CHEMBL5094597)
Affinity DataIC50:  10nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant LYN using biotinyl-beta amyloid beta amyloid beta AKVEKIGEGTYGVVYK as substrate measured after 120 mins in the presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583438(CHEMBL5091093)
Affinity DataIC50:  10nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583431(CHEMBL5075663)
Affinity DataIC50:  10nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  10nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583427(CHEMBL5094597)
Affinity DataIC50:  12nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583432(CHEMBL5075281)
Affinity DataIC50:  12nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583431(CHEMBL5075663)
Affinity DataIC50:  13nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583443(CHEMBL5078526)
Affinity DataIC50:  13nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583444(CHEMBL5087251)
Affinity DataIC50:  13nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583441(CHEMBL5082590)
Affinity DataIC50:  15nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583432(CHEMBL5075281)
Affinity DataIC50:  15nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human JAK3 using Ulight-CAGAGAIETDKEYYTVKD as substrate incubate for 60 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583437(CHEMBL5087106)
Affinity DataIC50:  17nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50583448(CHEMBL5091163)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583433(CHEMBL5078528)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50:  20nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
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