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Found 44 with Last Name = 'peppard' and Initial = 'j'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042828(4-Hydroxy-1-(9-mercaptomethyl-10-oxo-azecane-2-car...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042835(1-(9-Mercaptomethyl-10-oxo-azecane-2-carbonyl)-pyr...)
Affinity DataIC50:  2nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042827(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042827(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381090(CHEMBL2017551)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50:  10.9nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042832(3-Hydroxy-2-[(9-mercaptomethyl-10-oxo-azecane-2-ca...)
Affinity DataIC50:  11nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042831(6-Amino-2-[(9-mercaptomethyl-10-oxo-azecane-2-carb...)
Affinity DataIC50:  14nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50:  39.2nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50:  55.7nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042830(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  59nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042829(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  63nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  63.9nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50:  66.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  73.8nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50:  77.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042836(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  84nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313603(2-(cyclopropanecarboxamido)-5-(methyl(pyridin-3-yl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381090(CHEMBL2017551)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50:  162nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50:  186nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381095(CHEMBL2017550)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  203nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042834(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  209nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  241nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50:  287nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381096(CHEMBL2017556)
Affinity DataIC50:  358nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  441nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313601(2-(2-((5-(2-chlorophenyl)furan-2-yl)methylene)hydr...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042833(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50:  551nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313600(2-(3-(3,5-dichlorophenyl)ureido)benzoic acid | 2-{...)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  939nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042827(9-Mercaptomethyl-10-oxo-azecane-2-carboxylic acid ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381097(CHEMBL2017557)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313602(5-(methyl(pyridin-3-ylmethyl)amino)-2-propionamido...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant human DHODH by using blue indicator dye DCIPMore data for this Ligand-Target Pair