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Found 33 with Last Name = 'perez' and Initial = 'ag'
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320996(6-(3-((S)-1-methoxypropan-2-yloxy)-5-((S)-1-phenyl...)
Affinity DataEC50:  45nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346030((S)-3-cyclopentyl-N-(5-methylpyrazin-2-yl)-2-(4-(m...)
Affinity DataEC50:  3.50E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346001((S)-3-cyclopentyl-2-(4-(cyclopropylsulfonyl)-2-oxo...)
Affinity DataEC50:  110nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346002((S)-2-(3-chloro-4-(isopropylsulfonyl)-2-oxopyridin...)
Affinity DataEC50:  70nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346003((S)-2-(5-chloro-4-(methylsulfonyl)-2-oxopyridin-1(...)
Affinity DataEC50:  140nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346004((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-5-methy...)
Affinity DataEC50:  160nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346005((S)-3-(4,4-difluorocyclohexyl)-2-(4-(isopropylsulf...)
Affinity DataEC50:  160nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251391((2R)-2-(4-Cyclopropanesulfonylphenyl)-N-(5-fluorot...)
Affinity DataEC50:  180nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346006((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  230nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346007((S)-3-cyclohexyl-2-(4-(isopropylsulfonyl)-2-oxopyr...)
Affinity DataEC50:  240nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346008((S)-2-(5-chloro-4-(isopropylsulfonyl)-2-oxopyridin...)
Affinity DataEC50:  260nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346009((S)-2-(4-(cyclobutylsulfonyl)-2-oxopyridin-1(2H)-y...)
Affinity DataEC50:  260nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346010((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  330nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346011((S)-3-cyclopentyl-2-(5-methyl-4-(methylsulfonyl)-2...)
Affinity DataEC50:  440nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346012((S)-3-cyclopentyl-2-(4-(ethylsulfonyl)-2-oxopyridi...)
Affinity DataEC50:  500nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346013((S)-2-(5-chloro-4-(methylsulfonyl)-2-oxopyridin-1(...)
Affinity DataEC50:  480nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346014((S)-2-(4-(isopropylsulfonyl)-2-oxopyridin-1(2H)-yl...)
Affinity DataEC50:  510nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346015((S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-(4-(m...)
Affinity DataEC50:  560nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346016((S)-2-(4-(cyclobutylsulfonyl)-2-oxopyridin-1(2H)-y...)
Affinity DataEC50:  590nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346017((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  600nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346018(2-amino-4-fluoro-5-(1-methyl-1H-imidazol-2-ylthio)...)
Affinity DataEC50:  620nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346019((S)-3-cyclobutyl-2-(4-(isopropylsulfonyl)-2-oxopyr...)
Affinity DataEC50:  670nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataEC50:  690nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346021((S)-2-(5-chloro-4-(isopropylsulfonyl)-2-oxopyridin...)
Affinity DataEC50:  700nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346022((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  720nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346023((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  910nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346024((S)-3-cyclopentyl-2-(4-(cyclopropylsulfonyl)-2-oxo...)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346025((S)-3-cyclopentyl-2-(4-(isopropylsulfonyl)-2-oxopy...)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346026((R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-((R)-3...)
Affinity DataEC50:  1.42E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346027((S)-2-(4-(ethylsulfonyl)-2-oxopyridin-1(2H)-yl)-N-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346028((S)-3-cyclopentyl-2-(4-(cyclopropylsulfonyl)-2-oxo...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346029((S)-2-(4-(isopropylsulfonyl)-2-oxopyridin-1(2H)-yl...)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50346000((S)-2-(4-(cyclobutylsulfonyl)-2-oxopyridin-1(2H)-y...)
Affinity DataEC50:  60nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed