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Found 217 with Last Name = 'popowycz' and Initial = 'f'
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168997(4-Fluoro-benzoic acid 2-[((2R,3R,4S)-3,4-dihydroxy...)
Affinity DataKi:  19nMAssay Description:Binding affinity against alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235671(CHEMBL4097212)
Affinity DataKi:  20nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235667(CHEMBL4080688)
Affinity DataKi:  20nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235661(CHEMBL4088796)
Affinity DataKi:  20nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235670(CHEMBL4079988)
Affinity DataKi:  30nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235673(CHEMBL4060572)
Affinity DataKi:  50nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235668(CHEMBL4098946)
Affinity DataKi:  50nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235672(CHEMBL4061606)
Affinity DataKi:  60nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  71.9nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339680(CHEMBL1688930 | S-(2-Methyl-1,1-diphenylbutyl)-L-c...)
Affinity DataKi:  76.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339673(CHEMBL1688927 | S-(1,1-Diphenyl[4-(butyl)phenyl]me...)
Affinity DataKi:  84.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235674(CHEMBL4070018)
Affinity DataKi:  90nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235664(CHEMBL4083422)
Affinity DataKi:  90nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)
Affinity DataKi:  98.6nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235665(CHEMBL4104227)
Affinity DataKi:  100nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)
Affinity DataKi:  156nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)
Affinity DataKi:  175nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM768(4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one | CH...)
Affinity DataKi:  200nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235669(CHEMBL4080910)
Affinity DataKi:  200nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235663(CHEMBL4070271)
Affinity DataKi:  260nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339681(CHEMBL1688931 | S-(2-Ethyl-1,1-diphenylbutyl)-L-cy...)
Affinity DataKi:  302nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339672(CHEMBL1688926 | S-(1,1-Diphenyl[4-(tert-butyl)phen...)
Affinity DataKi:  429nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168999((2R,3R,4R,5R)-5-(Benzylamino-methyl)-pyrrolidine-2...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339671(CHEMBL1688925 | S-(1,1-Diphenyl[4-biphenyl]methyl)...)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168991((2R,3S,4R,5R)-2-Hydroxymethyl-5-[((R)-2-hydroxy-1-...)
Affinity DataKi:  1.35E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168998((2R,3R,4S)-2-((R)-Indan-1-ylaminomethyl)-pyrrolidi...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339679(4-((2-amino-2-carboxyethylthio)diphenylmethyl)benz...)
Affinity DataKi:  2.54E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339670(CHEMBL1688924 | S-(1,1-Diphenyl[4-(cyclohexyl)phen...)
Affinity DataKi:  3.26E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235662(CHEMBL4091210)
Affinity DataKi:  3.90E+3nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168993((2R,3R,4S)-2-(Benzylamino-methyl)-pyrrolidine-3,4-...)
Affinity DataKi:  7.40E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50104307(2-(Benzylamino-methyl)-pyrrolidine-3,4-diol | CHEM...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibitory activity towards Alpha-mannosidase from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase(Prunus avium)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104303(2-{[(Furan-2-ylmethyl)-amino]-methyl}-pyrrolidine-...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50169000((2R,3R,4S)-2-[((R)-2-Benzyloxy-1-phenyl-ethylamino...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from Caldocellum saccharol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50402977(CHEMBL2207397)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from Caldocellum saccharolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104295(2-[(2-Hydroxy-1-methyl-2,2-diphenyl-ethylamino)-me...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity towards Beta-galactosidase from Bovine liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50235666(CHEMBL4104918)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168994(2-Fluoro-benzoic acid 2-[((2R,3R,4S)-3,4-dihydroxy...)
Affinity DataKi:  2.40E+4nMAssay Description:Binding affinity against alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104296(2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibitory activity towards Beta-galactosidase from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50104298(2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-pyrrolidi...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from Caldocellum saccharolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104296(2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from Caldocellum saccharolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase(Prunus avium)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50104296(2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHE...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50402978(CHEMBL2207396)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibitory activity towards Alpha-mannosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucoamylase 1(Rhizopus oryzae)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataKi:  4.40E+4nMAssay Description:Inhibitory activity towards Alpha-glucosidase from Rhizopus mold (amyloglucosidase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase(Prunus avium)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50402977(CHEMBL2207397)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50104306(2-Aminomethyl-pyrrolidine-3,4-diol | CHEMBL79727)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibitory activity towards Alpha-mannosidase from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucosidase(Prunus avium)
Section De Chimie De L'Universit£

Curated by ChEMBL
LigandPNGBDBM50403869(CHEMBL2115197)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibitory activity towards Beta-Glucosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339682((R)-2-amino-3-(diphenyl(thiophen-2-yl)methylthio)p...)
Affinity DataKi:  5.83E+4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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