Affinity DataKi: 0.00500nMAssay Description:Competitive reversible inhibition of human C-terminal His6-tagged CD73 expressed in HEK293 cells using AMP as substrate preincubated with substrate f...More data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in HEK293 cells using AMP as substrate preincubated for 1 h...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of PI3Kgamma (unknown origin) at 10 uM using PIP2 as substrate preincubated for 60 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human 11beta-HSD1 using variable cofactor NADPH concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human 11beta-HSD1 using variable substrate cortisol concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Inhibition of human CD73 using AMP as substrate by Malachite green phosphate reagent-based assayMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rattus norvegicus)
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 328nMAssay Description:Inhibition of rat CD39 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
Affinity DataKi: 374nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 510nMAssay Description:Inhibition of CD73 in human melanoma 1539 cells using AMP substrate by capillary electrophoresis assayMore data for this Ligand-Target Pair
Affinity DataKi: 608nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Dixon and ...More data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Cheng-Prus...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Inhibition of rat CD73 expressed in baculovirus infected insect cells using AMP substrate by capillary electrophoresis assayMore data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 900nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Dixon and ...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Competitive inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins by Dixo...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Competitive inhibition of human NPP1 using pnp-TMP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins by ...More data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rattus norvegicus)
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 1.57E+4nMAssay Description:Inhibition of rat CD39 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rattus norvegicus)
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 3(Homo sapiens (Human))
Arcus Biosciences
Curated by ChEMBL
Arcus Biosciences
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Competitive inhibition of human NTPDase3 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins by ...More data for this Ligand-Target Pair