Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0186nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0260nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0340nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0420nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0430nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0510nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0530nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.0620nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair