TargetPlatelet-activating factor receptor(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]-PAF from PAF receptor of human platelet membranesMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK2alpha2 (unknown origin) by by exchange curve binding kinetic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human HDAC1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Dongguan Zhenxing-Beite Medicine Technology
US Patent
Affinity DataIC50: 4.60nMAssay Description:In the case of Km ATP, EGFR T790M/L858R protein kinase activity was tested by Caliper mobility shift assay (referring to J Biomol Screen 14:31, 2009)...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human HDAC6 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 10 mins followed by Ac-Leu-GlyLys(Ac)-AMC substrate addition measured after 30 mins by fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Jnk2alpha2More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]-PAF from PAF receptor of human platelet membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of 5-lipoxygenase in RBL-2H3 (Rat basophilic leukaemia) cells.More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:In vitro affinity for human PAF receptor on platelet membranes using [3H]-PAF displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 10 mins followed by Ac-Leu-GlyLys(Ac)-AMC substrate addition measured after 30 mins by fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human HDAC3 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-PAF from PAF receptor of human platelet membranesMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC5 expressed in Escherichia coliMore data for this Ligand-Target Pair