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Found 41 with Last Name = 'rafiq' and Initial = 'm'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataKi:  1.10E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108112(CHEMBL3601648)
Affinity DataKi:  1.30E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-inhibitor dissociation constant preincubated for 10 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108113(CHEMBL3601649)
Affinity DataKi:  4.10E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-inhibitor dissociation constant preincubated for 10 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108112(CHEMBL3601648)
Affinity DataKi:  5.30E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-substrate-inhibitor dissociation constant preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108114(CHEMBL3601650)
Affinity DataKi:  6.00E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-inhibitor dissociation constant preincubated for 10 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108109(CHEMBL3601645)
Affinity DataKi:  6.50E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-inhibitor dissociation constant preincubated for 10 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108113(CHEMBL3601649)
Affinity DataKi:  1.00E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-substrate-inhibitor dissociation constant preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataKi:  1.30E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108109(CHEMBL3601645)
Affinity DataKi:  2.05E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as enzyme-substrate-inhibitor dissociation constant preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178021((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  58nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178020((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  64nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178016((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  72nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178019((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  81nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178022((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  83nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178017((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  83nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178015((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  87nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178014((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  87nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178013((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  96nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM178018((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50:  350nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50139369(2-Hydroxy-4-isopropyl-benzaldehyde | CHEMBL353354)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108112(CHEMBL3601648)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Quaid-I-Azam University

LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataIC50:  2.09E+4nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108114(CHEMBL3601650)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108113(CHEMBL3601649)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511057(CHEMBL4437587)
Affinity DataIC50:  3.94E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108109(CHEMBL3601645)
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108111(CHEMBL3601647)
Affinity DataIC50:  5.98E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108107(CHEMBL3601643)
Affinity DataIC50:  7.89E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108115(CHEMBL3601651)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511063(CHEMBL4452349)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108110(CHEMBL3601646)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511061(CHEMBL4439676)
Affinity DataIC50:  1.73E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511059(CHEMBL4468115)
Affinity DataIC50:  1.93E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50108108(CHEMBL3601644)
Affinity DataIC50:  2.01E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511060(CHEMBL4582859)
Affinity DataIC50:  2.99E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511062(CHEMBL4448917)
Affinity DataIC50:  3.15E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511055(CHEMBL4519402)
Affinity DataIC50:  3.38E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed