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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50104923(CHEMBL3597643)

Ki: 0.118nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50105009(CHEMBL3597645)

Ki: 0.128nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533609(CHEMBL4544583)

Ki: 0.142nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533620(CHEMBL4476699)

Ki: 0.153nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL

BDBM25391(CHEMBL200622 | SB-590885 | SB590885 | [2-(4-{4-[(1...)

Ki: 0.160nMAssay Description:Inhibition of N-terminus His-6 tagged human B-Raf expressed in baculovirus infected insect Sf9 cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50104998(CHEMBL3597644)

Ki: 0.173nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533625(CHEMBL4552939)

Ki: 0.200nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50097834(CHEMBL3589652)

Ki: 0.233nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair

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PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50105004(CHEMBL3596212)

Ki: 0.244nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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D(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50007518((S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)me...)

Ki: 0.260nMAssay Description:Displacement of [3H]N-methylspiperone from human D2R expressed in HEK293 cell membranes incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair

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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50129425(5-Fluoro-1H-indole-2-carboxylic acid {4-[4-(2,3-di...)

Ki: 0.280nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530563(CHEMBL4519938 | US11337971, Compound (R)-19)

Ki: 0.290nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530563(CHEMBL4519938 | US11337971, Compound (R)-19)

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL

BDBM50104925(CHEMBL3597635)

Ki: 0.330nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533617(CHEMBL4555307)

Ki: 0.331nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533621(CHEMBL4521947)

Ki: 0.341nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50104925(CHEMBL3597635)

Ki: 0.351nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530577(CHEMBL4451683 | US11337971, Compound (+-)-19)

Ki: 0.362nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533612(CHEMBL4471669)

Ki: 0.363nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530572(CHEMBL4584497 | US11337971, Compound (R)-C5a)

Ki: 0.373nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530572(CHEMBL4584497 | US11337971, Compound (R)-C5a)

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50104927(CHEMBL3597641)

Ki: 0.392nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530577(CHEMBL4451683 | US11337971, Compound (+-)-19)

Ki: 0.433nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530577(CHEMBL4451683 | US11337971, Compound (+-)-19)

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50342720((R)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-...)

Ki: 0.530nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50105140(CHEMBL3597639)

Ki: 0.570nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

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PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533624(CHEMBL4461461)

Ki: 0.621nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530570(CHEMBL4515234 | US11337971, Compound C5a)

Ki: 0.756nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530570(CHEMBL4515234 | US11337971, Compound C5a)

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530573(CHEMBL4446609 | US11337971, Compound (S)-C5a)

Ki: 0.840nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530573(CHEMBL4446609 | US11337971, Compound (S)-C5a)

PDB Reactome pathway KEGG
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D(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50515232(CHEMBL4471817)

Ki: 0.844nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530564(CHEMBL4483569 | US11337971, Compound (S)-19)

Ki: 0.886nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50530564(CHEMBL4483569 | US11337971, Compound (S)-19)

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50104928(CHEMBL3597642)

Ki: 0.907nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 1 hr by liquid scintillation ...More data for this Ligand-Target Pair

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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533615(CHEMBL4577414)

Ki: 0.941nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533619(CHEMBL4517102)

Ki: 0.985nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50097841(CHEMBL3588919)

Ki: 1nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Glutamate carboxypeptidase 2(Homo sapiens (Human))
Johns Hopkins School Of Medicine

Curated by ChEMBL

BDBM50392045(CHEMBL2152561)

Ki: 1nMAssay Description:Inhibition of GCP-2 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533623(CHEMBL4543524)

Ki: 1.10nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

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Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL

BDBM50540117(CHEMBL4641869)

Ki: 1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in guinea pig cortex membranes incubated for 120 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair

Reactome pathway KEGG
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Sodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL

BDBM50540118(CHEMBL4642082)

Ki: 1.30nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Sodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL

BDBM50540121(CHEMBL4649604)

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50116766((-)-Pramipexole | (6S)-N(6)-propyl-4,5,6,7-tetrahy...)

Ki: 1.30nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta scin...More data for this Ligand-Target Pair

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3D Structure (crystal)

D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50533610(CHEMBL4564507)

Ki: 1.30nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c...More data for this Ligand-Target Pair

PDB Reactome pathway
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PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50097780(CHEMBL3588987)

Ki: 1.40nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair

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PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50097849(CHEMBL3588986)

Ki: 1.5nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair

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Sodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL

BDBM50540114(CHEMBL4647914)

Ki: 1.5nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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D(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL

BDBM50097836(CHEMBL3588914)

Ki: 1.60nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair

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