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Found 42 with Last Name = 'rallapalli' and Initial = 's'
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  5.30nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  5.40nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi:  7.40nM ΔG°:  -43.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  13.8nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  15nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  21.4nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  25.8nM ΔG°:  -40.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.4nM ΔG°:  -40.0kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  28.8nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  45nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  54.2nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25882(XLi374, 5 | [({12-ethynyl-8-methyl-9-oxo-2,4,8-tri...)
Affinity DataKi:  76.1nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  96nM ΔG°:  -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  101nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi:  194nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  231nM ΔG°:  -35.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi:  236nM ΔG°:  -35.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi:  272nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  287nM ΔG°:  -34.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25884(2-[2-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8....)
Affinity DataKi:  460nM ΔG°:  -33.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  661nM ΔG°:  -32.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  858nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  1.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  1.50E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  1.55E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  1.85E+3nM ΔG°:  -30.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25882(XLi374, 5 | [({12-ethynyl-8-methyl-9-oxo-2,4,8-tri...)
Affinity DataKi:  1.86E+3nM ΔG°:  -30.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi: >2.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  2.67E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25882(XLi374, 5 | [({12-ethynyl-8-methyl-9-oxo-2,4,8-tri...)
Affinity DataKi:  2.69E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25882(XLi374, 5 | [({12-ethynyl-8-methyl-9-oxo-2,4,8-tri...)
Affinity DataKi:  3.80E+3nM ΔG°:  -28.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  4.70E+3nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi: >5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi: >5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25884(2-[2-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8....)
Affinity DataKi:  5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25884(2-[2-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8....)
Affinity DataKi:  5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25884(2-[2-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8....)
Affinity DataKi:  5.00E+3nM ΔG°:  -28.1kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  8.55E+3nM ΔG°:  -26.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed