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Found 126 with Last Name = 'ramírez' and Initial = 'jl'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303711(3,4-Difluoro-N-{(E)-3-[5-fluoro-1-(3-methoxybenzyl...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303663(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(CHEMBL585581 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303660(CHEMBL566005 | N-{(E)-3-[1-(2,4-Dichlorobenzyl)-5-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(CHEMBL585581 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303677(CHEMBL566016 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303709(3,4-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303680(4,5-Dichlorothiophene-2-sulfonic Acid[3-(3-Naphtha...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303682(4,5-Dichloro-thiophene-2-sulfonic acid{3-[5-fluoro...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303679(4,5-Dichlorothiophene-2-sulfonic Acid[3-(1-Methyl-...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303681(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(1-Met...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303667(CHEMBL566221 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303676(4,5-Dichloro-thiophene-2-sulfonic acid[3-(1-methyl...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303707(3,5-Difluoro-N-[(E)-3-(5-fluoro-1-imidazo[1,2-a]py...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303665(4,5-Dichlorothiophene-2-sulfonic Acid{(E)-3-[1-(3-...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303670((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303693(CHEMBL585099 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303712(2,4,5-Trifluoro-N-{(E)-3-[5-fluoro-1-(3-methoxyben...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303664(4,5-Dichlorothiophene-2-sulfonic Acid{(E)-3-[1-(4-...)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303674(4,5-Dichloro-thiophene-2-sulfonic acid{2-[3-(napht...)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303715(CHEMBL565791 | N-{(E)-3-[1-(2,4-Dichlorobenzyl)-5-...)
Affinity DataIC50:  13.8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303690(CHEMBL566015 | Thiophene-2-sulfonic Acid[(E)-3-(1-...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303668(CHEMBL566631 | Thiophene-2-sulfonic Acid[(E)-3-(5-...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303696(CHEMBL565597 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  14.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303710(CHEMBL566643 | N-{(E)-3-[1-(3,5-Dimethylisoxazol-4...)
Affinity DataIC50:  14.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303669(CHEMBL567266 | Naphthalene-2-carboxylic acid{4-[(E...)
Affinity DataIC50:  14.6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303678(CHEMBL585100 | Thiophene-2-sulfonic acid [3-(5-flu...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303689(CHEMBL585091 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303672(CHEMBL565604 | Thiophene-2-sulfonic acid [2-(1-nap...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303671(CHEMBL585582 | Naphthalene-2-carboxylic acid{4-[(E...)
Affinity DataIC50:  27.6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(CHEMBL585581 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303686(CHEMBL584495 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50:  36nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303673(CHEMBL567484 | Thiophene-2-sulfonic acid{(E)-3-[1-...)
Affinity DataIC50:  36nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303688(CHEMBL584279 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  42nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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