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Found 410 with Last Name = 'ram' and Initial = 'mk'
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132351(({4-[6-(2,6-Dichloro-phenyl)-8-(3-dimethylamino-pr...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  1nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  1nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  1nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086083(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437403(CHEMBL2408771)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086090(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50:  1.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)
Affinity DataIC50:  2nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132348(({4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-di...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  2nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  3nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086094(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132322(({2-[(2-{4-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086077(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50:  4.40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
University Of Helsinki

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086092(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50:  5.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  6nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437395(CHEMBL2408638)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  7nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427742(CHEMBL2324930)
Affinity DataIC50:  8nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  9nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437395(CHEMBL2408638)
Affinity DataIC50:  9nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427748(CHEMBL2324925)
Affinity DataIC50:  10nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437404(CHEMBL2408655)
Affinity DataIC50:  11nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  11nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427747(CHEMBL2324926)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427745(CHEMBL2324927)
Affinity DataIC50:  12nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Ariad Gene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50086078(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50:  12nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427741(CHEMBL2324931)
Affinity DataIC50:  13nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427744(CHEMBL2324928)
Affinity DataIC50:  14nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427742(CHEMBL2324930)
Affinity DataIC50:  15nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427750(CHEMBL2324923)
Affinity DataIC50:  15nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM3071(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 38 | 2-ani...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437396(CHEMBL2408651)
Affinity DataIC50:  16nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437402(CHEMBL2408774)
Affinity DataIC50:  17nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50437396(CHEMBL2408651)
Affinity DataIC50:  17nMAssay Description:Inhibition of porcine DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic

Curated by ChEMBL
LigandPNGBDBM50427741(CHEMBL2324931)
Affinity DataIC50:  18nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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