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Found 66 with Last Name = 'randall' and Initial = 'cp'
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286774(CHEMBL4163140)
Affinity DataIC50:  13nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286767(CHEMBL4172643)
Affinity DataIC50:  14nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286765(CHEMBL4159778)
Affinity DataIC50:  23nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286770(CHEMBL4171058)
Affinity DataIC50:  32nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286775(CHEMBL4174152)
Affinity DataIC50:  33nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286772(CHEMBL4160841)
Affinity DataIC50:  35nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286766(CHEMBL4163450)
Affinity DataIC50:  41nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286771(CHEMBL4167692)
Affinity DataIC50:  47nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286769(CHEMBL4161986)
Affinity DataIC50:  54nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286768(CHEMBL4171458)
Affinity DataIC50:  65nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286766(CHEMBL4163450)
Affinity DataIC50:  160nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286768(CHEMBL4171458)
Affinity DataIC50:  220nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286775(CHEMBL4174152)
Affinity DataIC50:  224nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286767(CHEMBL4172643)
Affinity DataIC50:  490nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286770(CHEMBL4171058)
Affinity DataIC50:  640nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286767(CHEMBL4172643)
Affinity DataIC50:  650nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286765(CHEMBL4159778)
Affinity DataIC50:  850nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286774(CHEMBL4163140)
Affinity DataIC50:  920nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286768(CHEMBL4171458)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286773(CHEMBL4174897)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei LeuRS assessed as reduction in protein synthesis pretreated for 20 mins in presence of [14C]Leu followed by ATP addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286772(CHEMBL4160841)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286774(CHEMBL4163140)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286765(CHEMBL4159778)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286771(CHEMBL4167692)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286771(CHEMBL4167692)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286770(CHEMBL4171058)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286775(CHEMBL4174152)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286769(CHEMBL4161986)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286766(CHEMBL4163450)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286773(CHEMBL4174897)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human cytoplasmic LeuRS assessed as reduction in protein synthesis measured after 10 mins in presence of [3H]Leu by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286772(CHEMBL4160841)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design

Curated by ChEMBL
LigandPNGBDBM50286769(CHEMBL4161986)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447032(CHEMBL3116334)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447035(CHEMBL3116331)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447044(CHEMBL3112645)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447037(CHEMBL3116329)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447048(CHEMBL3112637)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447036(CHEMBL3116330)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447033(CHEMBL3116333)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447050(CHEMBL3112632)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447049(CHEMBL3112633)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447045(CHEMBL3112644)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447040(CHEMBL3116326)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447038(CHEMBL3116328)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447034(CHEMBL3116332)
Affinity DataIC50:  1.17E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447041(CHEMBL3112648)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447043(CHEMBL3112646)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447055(CHEMBL3112590)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447052(CHEMBL3112630)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447046(CHEMBL3112640)
Affinity DataIC50:  1.54E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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