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Found 647 with Last Name = 'reddy' and Initial = 'dr'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Tyrosine-protein kinase receptor FLT3 (fms-related tyrosine kinase 3) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50328678(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human KDAC6 expressed in baculovirus expression system using FITC-Histone 4 acetylated peptide as substrate after 60 mins by microfluid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136019(9-ethoxymethyl-12-(3-hydroxypropyl)-6,7,12,13-tetr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50328678(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of full length human C-terminal His-tagged KDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) expressed in baculovirus expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50239022(CHEMBL4099599)
Affinity DataIC50:  7nMAssay Description:Inhibition of full length human C-terminal His-tagged KDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) expressed in baculovirus expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50239022(CHEMBL4099599)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of full length human C-terminal FLAG/His-tagged KDAC1 expressed in baculovirus expression system using substrate A after 60 mins by microf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136018(9-(tert-butoxymethyl)-12-(3-hydroxypropyl)-6,7,12,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50024274(CHEMBL2448133)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136013(9-(sec-butoxymethyl)-12-(3-hydroxypropyl)-6,7,12,1...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136021(12-(3-hydroxypropyl)-9-propoxymethyl-6,7,12,13-tet...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136017(12-(3-hydroxypropyl)-9-methoxymethyl-6,7,12,13-tet...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136015(9-butoxymethyl-12-(3-hydroxypropyl)-6,7,12,13-tetr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136024(3-(9-isopropoxymethyl-5-oxo-6,7,12,13-tetrahydro-5...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50024273(CHEMBL2112040)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human KDAC1 using substrate A after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136022(9-ethylsulfanylmethyl-12-(3-hydroxypropyl)-6,7,12,...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136020(9-(1-ethylpropoxymethyl)-12-(3-hydroxypropyl)-6,7,...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136030(12-(3-hydroxypropyl)-6,7,12,13-tetrahydro-5H-inden...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136031(9-isopropoxymethyl-6,7,12,13-tetrahydro-5H-indeno[...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of Proto-oncogene tyrosine-protein kinase KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136028(12-(3-hydroxypropyl)-9-isopropylsulfanylmethyl-6,7...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human KDAC3 using FITC-labeled p53 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50:  68nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50328678(6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexa...)
Affinity DataIC50:  71nMAssay Description:Inhibition of full length human C-terminal FLAG/His-tagged KDAC1 expressed in baculovirus expression system using substrate A after 60 mins by microf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136016(12-(3-hydroxypropyl)-9-(1-methoxyethyl)-6,7,12,13-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164518(CHEMBL3800394)
Affinity DataIC50:  76nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164531(CHEMBL3799246)
Affinity DataIC50:  91nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50:  95nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136025(9-bromo-12-(3-hydroxypropyl)-6,7,12,13-tetrahydro-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136033(12-(3-hydroxypropyl)-5-oxo-6,7,12,13-tetrahydro-5H...)
Affinity DataIC50:  105nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164519(CHEMBL3799297)
Affinity DataIC50:  107nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136012(12-(2-hydroxyethyl)-6,7,12,13-tetrahydro-5H-indeno...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM14177(3,13-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136010(9-(1-hydroxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-...)
Affinity DataIC50:  111nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164538(CHEMBL3797597)
Affinity DataIC50:  117nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164522(CHEMBL3797442)
Affinity DataIC50:  120nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164515(CHEMBL3798028)
Affinity DataIC50:  129nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human KDAC6 using FITC-labeled histone H4 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136029(9-(1-butoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164514(CHEMBL3799728)
Affinity DataIC50:  138nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164520(CHEMBL3798503)
Affinity DataIC50:  145nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50:  148nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50:  151nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136008(12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-...)
Affinity DataIC50:  162nMAssay Description:Inhibition of Fibroblast growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50136023(9-methyl-12-(3-hydroxypropyl)-6,7,12,13-tetrahydro...)
Affinity DataIC50:  163nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50164597(CHEMBL3798925)
Affinity DataIC50:  178nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50233043(CHEMBL4084736)
Affinity DataIC50:  180nMAssay Description:Inhibition of human KDAC3 using FITC-labeled p53 acetylated peptide as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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