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Found 34 with Last Name = 'reilly' and Initial = 'ca'
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.00E+3nMAssay Description:Negative allosteric modulation activity at human GABAA alpha4beta3gamma2 stably expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-1/beta-1/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.50E+3nMAssay Description:Negative allosteric modulation activity at human GABAA alpha1beta1gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040096(CHEMBL3359452)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM22987((5Z,8Z,11Z,14Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  5.50E+3nMAssay Description:Negative allosteric modulation activity at human GABAA alpha3beta3gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040096(CHEMBL3359452)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040098(CHEMBL3359450)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040097(CHEMBL3359453)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040098(CHEMBL3359450)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040097(CHEMBL3359453)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040096(CHEMBL3359452)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM22987((5Z,8Z,11Z,14Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040102(CHEMBL3359445)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040099(CHEMBL3359451)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040097(CHEMBL3359453)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.57E+4nMAssay Description:Negative allosteric modulation activity at human GABAA alpha2beta3gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM22987((5Z,8Z,11Z,14Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040099(CHEMBL3359451)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040103(CHEMBL3359446)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  1.94E+4nMAssay Description:Negative allosteric modulation activity at human GABAA alpha5beta3gamma2 stably expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50580362(CHEMBL5086854)
Affinity DataIC50:  2.10E+4nMAssay Description:Negative allosteric modulation activity at human GABAA alpha1beta3gamma2 stably expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040106(CHEMBL3359449)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040104(CHEMBL3359447)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040100(CHEMBL3359443)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040105(CHEMBL3359448)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50040101(CHEMBL3359444)
Affinity DataIC50:  2.03E+5nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Mus musculus)
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50345471((R)-N-((S)-1-((6S,9S,12R,13R,Z)-3-ethylidene-9-iso...)
Affinity DataIC50:  2.27E+5nMAssay Description:Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux by fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50345471((R)-N-((S)-1-((6S,9S,12R,13R,Z)-3-ethylidene-9-iso...)
Affinity DataIC50:  2.27E+5nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cell assessed as inhibition of capsaicin-induced calcium flux by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Mus musculus)
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50345472(CHEMBL1784750 | Nobilamide B)
Affinity DataIC50:  2.75E+5nMAssay Description:Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux by fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50345472(CHEMBL1784750 | Nobilamide B)
Affinity DataIC50:  2.75E+5nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cell assessed as inhibition of capsaicin-induced calcium flux by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Mus musculus)
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50345473((R)-2-((R)-2-acetamido-3-phenylpropanamido)-N-((S)...)
Affinity DataIC50:  1.32E+6nMAssay Description:Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux by fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50345473((R)-2-((R)-2-acetamido-3-phenylpropanamido)-N-((S)...)
Affinity DataIC50:  1.32E+6nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cell assessed as inhibition of capsaicin-induced calcium flux by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Mus musculus)
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50345474(CHEMBL1784749 | Nobilamide A)
Affinity DataIC50:  1.67E+6nMAssay Description:Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux by fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Roseman University Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50345474(CHEMBL1784749 | Nobilamide A)
Affinity DataIC50:  1.67E+6nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cell assessed as inhibition of capsaicin-induced calcium flux by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed