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Found 569 with Last Name = 'reinhard' and Initial = 'j'
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50016816(CHEMBL412913 | S-S-C-F-G-G-R-I-D-R-I-G-A-Q-S-G-L-G...)
Affinity DataKi:  0.25nMAssay Description:Apparent binding affinity for non-vasorelaxant receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355854(CHEMBL1909727)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355840(CHEMBL1912082)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355849(CHEMBL1909722)
Affinity DataKi:  2nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355844(CHEMBL1912087)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355847(CHEMBL1909720)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355852(CHEMBL1909725)
Affinity DataKi:  5.40nMAssay Description:Antagonist activity at rat NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355852(CHEMBL1909725)
Affinity DataKi:  7.60nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355839(CHEMBL1912081)
Affinity DataKi:  8nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355832(CHEMBL1912068)
Affinity DataKi:  12nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355859(CHEMBL1912086)
Affinity DataKi:  19nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355841(CHEMBL1912083)
Affinity DataKi:  31nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355848(CHEMBL1909721)
Affinity DataKi:  34nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355855(CHEMBL1909728)
Affinity DataKi:  38nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355833(CHEMBL1912071)
Affinity DataKi:  45nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355834(CHEMBL1912072)
Affinity DataKi:  49nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355858(CHEMBL1909731)
Affinity DataKi:  60nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  70nMAssay Description:Compound was tested for the binding affinity against bacterial kynureninaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355856(CHEMBL1909729)
Affinity DataKi:  75nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355825(CHEMBL1912074)
Affinity DataKi:  80nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355830(CHEMBL1912067)
Affinity DataKi:  109nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355836(CHEMBL1912078)
Affinity DataKi:  110nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355831(CHEMBL1912065)
Affinity DataKi:  150nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355826(CHEMBL1912075)
Affinity DataKi:  150nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355843(CHEMBL1912085)
Affinity DataKi:  159nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355857(CHEMBL1909730)
Affinity DataKi:  170nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355824(CHEMBL1912070)
Affinity DataKi:  170nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355838(CHEMBL1912080)
Affinity DataKi:  240nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355835(CHEMBL1912073)
Affinity DataKi:  250nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355850(CHEMBL1909723)
Affinity DataKi:  290nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355828(CHEMBL1912077)
Affinity DataKi:  360nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355845(CHEMBL1909718)
Affinity DataKi:  515nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355823(CHEMBL1912069)
Affinity DataKi:  530nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355829(CHEMBL1912066)
Affinity DataKi:  740nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355853(CHEMBL1909726)
Affinity DataKi:  803nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355842(CHEMBL1912084)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355846(CHEMBL1909719)
Affinity DataKi:  1.85E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355837(CHEMBL1912079)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355827(CHEMBL1912076)
Affinity DataKi:  4.30E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50355851(CHEMBL1909724)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  1.80E+4nMAssay Description:Compound was tested for the binding affinity against kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50140282(1-{4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...)
Affinity DataIC50:  0.280nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172695(CHEMBL370103 | {2-[3-((4R,5R)-3,3-Dibutyl-7-dimeth...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172649(1-{5-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50172702(4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hydrox...)
Affinity DataIC50:  0.75nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50370667(CHEMBL555246)
Affinity DataIC50:  0.760nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)
Affinity DataIC50:  0.770nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer with <1 nM [CETP] for 18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50452851(CHEMBL2373017)
Affinity DataIC50:  0.900nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049038(5-(4-Chloro-phenyl)-6-(4-methanesulfonyl-phenyl)-s...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049042(4-[6-(4-Trifluoromethyl-phenyl)-spiro[2.4]hept-5-e...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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