Affinity DataKi: 0.25nMAssay Description:Apparent binding affinity for non-vasorelaxant receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Antagonist activity at rat NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Compound was tested for the binding affinity against bacterial kynureninaseMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 109nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 159nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 515nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 803nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.85E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Binding affinity to human cloned NPY Y5 receptor expressed in african green monkey COS7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Compound was tested for the binding affinity against kynureninase in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer with <1 nM [CETP] for 18 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Concentration required to 50% inhibition in specific binding of [125- I]A-II to Angiotensin II receptor in rat uterine membraneMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair