TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by Hanes plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by Hanes plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 78nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 87nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 98nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair