TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: 423nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: 1.17E+3nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataKi: >8.00E+3nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.316nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at recombinant human CCR4 expressed in CHO-K1 cells assessed as inhibition of CCL22 induced Ca2+ mobilization after 2 hrs by FMAT...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Celltech R&D
Curated by ChEMBL
Celltech R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant phosphodiesterase 4AMore data for this Ligand-Target Pair