Compile Data Set for Download or QSAR
maximum 50k data
Found 42 with Last Name = 'sävmarker' and Initial = 'j'
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50157439(3-((2R,3S)-3-((S)-2-((S)-2-((S)-2-amino-3-(2H-tetr...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333404(3-(R)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333403(3-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333402(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  430nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333391(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  440nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297935(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((S)-1-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297934(2-Hydroxy-2-phenethyl-pentanedioic acid 1-[((1S,2R...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333406(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  680nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333397(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  870nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333405(3-(S)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297933((S)-2-Benzyl-2-hydroxy-pentanedioic acid 1-[((1S,2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333392(3-{3-[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297929(4-((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarba...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333388((S)-2-((S)-2-((S)-2-Amino-3-(2H-tetrazole-5-carbox...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297932((R)-2-Benzyl-2-hydroxy-pentanedioic acid 1-[((1S,2...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297927(2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297925(2-Benzyl-2-hydroxy-pentanedioic acid 5-[((S)-1-ben...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333401((4S,7S,10S)-4-Amino-14-hydroxy-10-isobutyl-7-isopr...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333409(3-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333410(3-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333407(3-(R)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333408(3-(S)-(2-{[(S)-2-((S)-2-{(S)-2-Amino-3-[(2H-tetraz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333394(3-(3-{(S)-2-[(S)-2-((R)-2-Amino-3-hydroxy-propiony...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333399(3-{3-[(S)-2-((S)-2-{(R)-3-Hydroxy-2-[(2H-tetrazole...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297931(4-((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarba...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297938(2-Benzyl-2-hydroxy-pentanedioic acid 1-{[3-[(R)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297928(4-[((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333398(3-{3-[(S)-2-((S)-2-{(R)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333400(3-{3-[(S)-2-((S)-2-{(S)-3-Hydroxy-2-[(2H-tetrazole...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297930(4-[((S)-2-{4-[3-[(R)-1-(4-Fluoro-phenyl)-ethylcarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333395(3-{3-[(S)-2-((S)-2-{(R)-2-Amino-3-[(2H-tetrazole-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333396(3-{2-Hydroxy-3-[(S)-2-((S)-2-{(R)-3-hydroxy-2-[(2H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333393(3-(3-{(S)-2-[(S)-2-((S)-2,3-Diamino-propionylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50297926(2-Hydroxy-2-phenethyl-pentanedioic acid 5-[((S)-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333413(3-[2-({(S)-2-[(S)-2-((S)-2,3-Diamino-propionylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333389(3-(2-Hydroxy-2-{[(S)-2-((S)-2-{(R)-3-hydroxy-2-[(2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333411(3-(2-{[(S)-2-((R)-3-{(S)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333412(3-(2-{[(S)-2-((S)-2-{(R)-2-Amino-3-[(2H-tetrazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50333390(3-(2-Hydroxy-2-{[(S)-2-((S)-2-{(S)-3-hydroxy-2-[(2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed