Compile Data Set for Download or QSAR
maximum 50k data
Found 74 with Last Name = 'sakuraba' and Initial = 's'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297070(CHEMBL560474 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297062(4-(5-chloropyridin-2-yl)-N-(2-cyclopropyl-3-methyl...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297073(CHEMBL564106 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30177(2-aminobenzimidazole-based compound, 25)
Affinity DataIC50:  2.70nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30172(2-aminobenzimidazole-based compound, 20)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297061(CHEMBL551934 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297059(CHEMBL561134 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297067(CHEMBL565105 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297071(CHEMBL562136 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30164(2-aminobenzimidazole-based compound, 12)
Affinity DataIC50:  4nM EC50:  22nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297068(CHEMBL551470 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297042(CHEMBL557731 | N-(2-methylimidazo[1,2-a]pyridin-6-...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297064(CHEMBL563728 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297052(CHEMBL563725 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297063(CHEMBL559680 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297041(CHEMBL557664 | N-(2-isopropylimidazo[1,2-a]pyridin...)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30174(2-aminobenzimidazole-based compound, 22)
Affinity DataIC50:  5.5nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297044(CHEMBL557730 | N-(2-cyclopropylimidazo[1,2-a]pyrid...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30156(2-aminobenzimidazole-based compound, 8)
Affinity DataIC50:  5.90nM EC50:  21nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297065(CHEMBL563096 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30165(2-aminobenzimidazole-based compound, 13)
Affinity DataIC50:  6.70nM EC50:  27nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297072(CHEMBL558826 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  6.80nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297045(CHEMBL549512 | N-(2-tert-butylimidazo[1,2-a]pyridi...)
Affinity DataIC50:  7.10nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297058(CHEMBL556432 | N-(2-cyclopropylimidazo[1,2-a]pyrid...)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30173(2-aminobenzimidazole-based compound, 21)
Affinity DataIC50:  8.80nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297043(CHEMBL554287 | N-(2-propylimidazo[1,2-a]pyridin-6-...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297055(CHEMBL562074 | N-(2-cyclopropyl-3-(hydroxymethyl)i...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30161(2-aminobenzimidazole-based compound, 9)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30176(2-aminobenzimidazole-based compound, 24)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297049(CHEMBL560334 | N-(2-(2-hydroxypropan-2-yl)imidazo[...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30162(2-aminobenzimidazole-based compound, 10)
Affinity DataIC50:  19nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297068(CHEMBL551470 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30168(2-aminobenzimidazole-based compound, 16)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30163(2-aminobenzimidazole-based compound, 11)
Affinity DataIC50:  24nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297061(CHEMBL551934 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297053(CHEMBL551332 | N-(2-cyclopropyl-3-ethylimidazo[1,2...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30166(2-aminobenzimidazole-based compound, 14)
Affinity DataIC50:  27nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297072(CHEMBL558826 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297048(CHEMBL556296 | N-(2-(1-hydroxyethyl)imidazo[1,2-a]...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30167(2-aminobenzimidazole-based compound, 15)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297051(CHEMBL551408 | N-(2-((N-methylacetamido)methyl)imi...)
Affinity DataIC50:  35nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM30171(2-aminobenzimidazole-based compound, 19)
Affinity DataIC50:  41nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their binding affinity to the membranes of CHO-K1 cells expressing human MCH1R (hMCH1R) in a competition binding assay w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297076(CHEMBL559801 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  44nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297066(CHEMBL563836 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  48nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297070(CHEMBL560474 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297075(CHEMBL558326 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  61nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297073(CHEMBL564106 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297050(CHEMBL563984 | N-(2-((dimethylamino)methyl)imidazo...)
Affinity DataIC50:  83nMAssay Description:Displacement of [125I]MCH from human MCH1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297064(CHEMBL563728 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50297063(CHEMBL559680 | N-(2-cyclopropyl-3-methylimidazo[1,...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human MCH1 receptor expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 74 total ) | Next | Last >>
Jump to: