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Found 206 with Last Name = 'salminen' and Initial = 'a'
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358746(CHEMBL596015)
Affinity DataKi:  2.90E+4nMAssay Description:Irreversible inhibition of CYP2A6 in human liver microsomes assessed as coumarin 7-hydroxylation activity by double reciprocal plot analysis in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
£Bo Akademi University

Curated by ChEMBL
LigandPNGBDBM50495406(CHEMBL3110302)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant VAP-1 transfected in CHO cells using 2,4-dichlorophenol/benzylamine as substrate incubated for 30 mins prior to benzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358746(CHEMBL596015)
Affinity DataIC50:  50nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
£Bo Akademi University

Curated by ChEMBL
LigandPNGBDBM50495407(CHEMBL3110303)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant VAP-1 transfected in CHO cells using 2,4-dichlorophenol/benzylamine as substrate incubated for 30 mins prior to benzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50342656(CHEMBL1770735 | benzo[b]thiophen-2-ylmethanamine)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257407(CHEMBL504310 | His-Lys-Lys(epsilon-thioAc)Ala-Met)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257289(CHEMBL505399 | Ser-Lys-Lys(epsilon-thioAc)Thr-Ile)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358752(CHEMBL1922273)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257348(CHEMBL492925 | Ser-Ala-Lys(epsilon-thioAc)Thr-Ile)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257345(CHEMBL510904 | His-Lys-Lys(epsilon-thioAc)Thr-Ile)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50326778((S)-2-((S)-2-((S)-2-Acetamidopropanamido)-6-ethane...)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50326778((S)-2-((S)-2-((S)-2-Acetamidopropanamido)-6-ethane...)
Affinity DataIC50:  240nMAssay Description:Inhibition of GST-SIRT1 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  280nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
£Bo Akademi University

Curated by ChEMBL
LigandPNGBDBM50495408(CHEMBL3110304)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant VAP-1 transfected in CHO cells using 2,4-dichlorophenol/benzylamine as substrate incubated for 30 mins prior to benzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(CHEMBL447677 | His-Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257286(CHEMBL521807 | Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(CHEMBL447677 | His-Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50326780((S)-2-((S)-2-((S)-2-Acetamidopropanamido)-6-ethane...)
Affinity DataIC50:  370nMAssay Description:Inhibition of GST-SIRT1 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355041(CHEMBL1835301)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257405(Ala-Lys-Lys(epsilon-thioAc)Leu-Met | CHEMBL504711)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355038(CHEMBL1835296)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257285(CHEMBL492308 | His-Lys-Lys(epsilon-thioAc)-Leu)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257406(CHEMBL453807 | His-Ala-Lys(epsilon-thioAc)Leu-Met)
Affinity DataIC50:  550nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257287(CHEMBL492309 | Lys-Lys(epsilon-thioAc)-Leu)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257287(CHEMBL492309 | Lys-Lys(epsilon-thioAc)-Leu)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358745(CHEMBL1922274)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355040(CHEMBL1835298)
Affinity DataIC50:  660nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50326779((S)-2-((S)-2-((S)-2-Acetamidopropanamido)-6-(3-met...)
Affinity DataIC50:  700nMAssay Description:Inhibition of GST-SIRT1 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355043(CHEMBL1835302)
Affinity DataIC50:  770nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257408(CHEMBL449883 | His-Lys-Lys(epsilon-thioAc)Leu-Ala)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355048(CHEMBL1835308)
Affinity DataIC50:  970nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355046(CHEMBL1835305)
Affinity DataIC50:  990nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355049(CHEMBL1835307)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355039(CHEMBL1835297)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50359740(CHEMBL1928092)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50359740(CHEMBL1928092)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355045(CHEMBL1835304)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355047(CHEMBL1835306)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257291(CHEMBL492710 | Ser-Asp-Lys(epsilon-thioAc)Thr-Met)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50359741(CHEMBL1928095)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358752(CHEMBL1922273)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50355053(CHEMBL1835312)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT1 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358746(CHEMBL596015)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50358745(CHEMBL1922274)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-SIRT1 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50355054(CHEMBL1835299)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT2 at 200 uM after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50359741(CHEMBL1928095)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50326781((S)-Benzyl 6-ethaneselenoamido-1-oxo-1-(phenylamin...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-SIRT2 after 1 hr by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50355038(CHEMBL1835296)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant GST-tagged SIRT2 after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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