Compile Data Set for Download or QSAR
maximum 50k data
Found 72 with Last Name = 'salzman' and Initial = 'a'
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8470800, A | US8609833, 17)
Affinity DataKi:  0.970nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97465(US8470800, B | US8609833, 85)
Affinity DataKi:  2.63nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108258(US8609833, 91)
Affinity DataKi:  4.05nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108256(CHEMBL2205239 | US8609833, 87)
Affinity DataKi:  5.79nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108257(US8609833, 88)
Affinity DataKi:  7nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97467(US8470800, D | US8609833, 93)
Affinity DataKi:  10.6nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108256(CHEMBL2205239 | US8609833, 87)
Affinity DataKi:  216nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97465(US8470800, B | US8609833, 85)
Affinity DataKi:  513nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8470800, A | US8609833, 17)
Affinity DataKi:  704nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108257(US8609833, 88)
Affinity DataKi:  900nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108256(CHEMBL2205239 | US8609833, 87)
Affinity DataKi:  951nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108258(US8609833, 91)
Affinity DataKi:  1.02E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97467(US8470800, D | US8609833, 93)
Affinity DataKi:  2.02E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97465(US8470800, B | US8609833, 85)
Affinity DataKi:  4.19E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97464(US8470800, A | US8609833, 17)
Affinity DataKi:  4.69E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108258(US8609833, 91)
Affinity DataKi:  9.11E+3nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM108257(US8609833, 88)
Affinity DataKi:  1.00E+4nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2(Homo sapiens (Human))
Inotek Pharmaceuticals

US Patent
LigandPNGBDBM97467(US8470800, D | US8609833, 93)
Affinity DataKi: >1.00E+5nMAssay Description:The affinities of selected Purine Derivatives for the adenosine A1 receptor were determined by measuring the displacement of specific [3H] 2-chloro-N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27525(N-[3-(morpholin-4-yl)propyl]-8-oxo-9-azatetracyclo...)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27528(13-fluoro-N-[3-(morpholin-4-yl)propyl]-8-oxo-9-aza...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322362(2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...)
Affinity DataIC50:  45nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27521(2-[4-(4-fluorophenyl)piperazin-1-yl]-N-{8-oxo-9-az...)
Affinity DataIC50:  80nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27515(14-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  98nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366893(CHEMBL607649)
Affinity DataIC50:  100nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27524(1-{8-oxo-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27522(4-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50:  105nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27520(2-(dimethylamino)-N-{8-oxo-9-azatetracyclo[8.7.0.0...)
Affinity DataIC50:  107nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27523(2-hydroxy-N-{8-oxo-9-azatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataIC50:  110nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366900(CHEMBL608792)
Affinity DataIC50:  250nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27511(14-nitro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27514(13-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27526(N-[3-(1H-imidazol-1-yl)propyl]-8-oxo-9-azatetracyc...)
Affinity DataIC50:  394nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27519(4-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50:  400nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366902(CHEMBL607648)
Affinity DataIC50:  450nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27529(13-fluoro-N-(morpholin-4-yl)-8-oxo-9-azatetracyclo...)
Affinity DataIC50:  450nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27530(13-fluoro-14-(1H-imidazole-1-sulfonyl)-9-azatetrac...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27512(13-fluoro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27510(13-nitro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27513(14-fluoro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]...)
Affinity DataIC50:  650nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366904(CHEMBL607928)
Affinity DataIC50:  700nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366895(CHEMBL607633)
Affinity DataIC50:  700nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27531(indeno[1,2-c]isoquinolinone, 13 | sodium 8-oxo-9-a...)
Affinity DataIC50:  700nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27532(4-methyl-4-[3-({8-oxo-9-azatetracyclo[8.7.0.0^{2,7...)
Affinity DataIC50:  800nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27516(2-(dimethylamino)-N-{8-oxo-9-azatetracyclo[8.7.0.0...)
Affinity DataIC50:  800nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366901(CHEMBL608232)
Affinity DataIC50:  900nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366897(CHEMBL607650)
Affinity DataIC50:  1.90E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366898(CHEMBL608784)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27517(2-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50: >3.00E+3nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366892(CHEMBL608783)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137371(2-Benzoimidazol-1-yl-N-(1-oxo-2,3-dihydro-1H-isoin...)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: