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Found 255 with Last Name = 'santi' and Initial = 's'
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  0.398nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.513nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M2) in guinea pig left atriaMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  0.589nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082769(CHEMBL3422790)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082777(CHEMBL3422784)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082768(CHEMBL3422788)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  2.80nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  3nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  4nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082776(CHEMBL3422785)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  4.40nMAssay Description:Compound was tested for binding affinity against Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  4.70nMAssay Description:Compound was tested for binding affinity against Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  5nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  6.5nMAssay Description:Compound was tested for inhibiting [3H]pirenzepine Binding to Muscarinic receptor (M1) receptor in Rat Cortex HomogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082772(CHEMBL3422791)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  10nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  10.5nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403484(CHEMBL306182)
Affinity DataKi:  11nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic acetylcholine receptor M4 in NG 108-15 CellMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082771(CHEMBL3422792)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  12nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082777(CHEMBL3422784)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082774(CHEMBL3422787)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082775(CHEMBL3422786)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403485(CHEMBL292857)
Affinity DataKi:  33nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat HeartMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  35nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082773(CHEMBL3422789)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082769(CHEMBL3422790)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  174nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082770(CHEMBL3422793)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB2 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082768(CHEMBL3422788)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187669(CHEMBL207208 | N-(4-methoxy-phenyl)-2-cyclopentyl-...)
Affinity DataKi:  410nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082774(CHEMBL3422787)
Affinity DataKi:  551nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082772(CHEMBL3422791)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  677nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082771(CHEMBL3422792)
Affinity DataKi:  702nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50011596((2-Cyclopentyl-1H-imidazo[4,5-c]quinolin-4-yl)-phe...)
Affinity DataKi:  786nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  794nMAssay Description:Evaluation of antagonistic affinity against muscarinic receptor (M3) in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082776(CHEMBL3422785)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187670(CHEMBL210380 | N-(4-methyl-phenyl)-2-cyclopentyl-1...)
Affinity DataKi:  1.19E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187671(CHEMBL378047 | N-(4-chloro-phenyl)-2-cyclopentyl-1...)
Affinity DataKi:  1.61E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082775(CHEMBL3422786)
Affinity DataKi:  2.61E+3nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50011596((2-Cyclopentyl-1H-imidazo[4,5-c]quinolin-4-yl)-phe...)
Affinity DataKi:  3.15E+3nMAssay Description:Displacement of [3H]R-PIA from human adenosine A2A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50011596((2-Cyclopentyl-1H-imidazo[4,5-c]quinolin-4-yl)-phe...)
Affinity DataKi:  3.42E+3nMAssay Description:Displacement of [3H]R-PIA from human adenosine A1 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50082773(CHEMBL3422789)
Affinity DataKi:  3.76E+3nMAssay Description:Displacement of [3H]-CP-55940 from recombinant human CB1 receptor overexpressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187670(CHEMBL210380 | N-(4-methyl-phenyl)-2-cyclopentyl-1...)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of [3H]R-PIA from human adenosine A1 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187669(CHEMBL207208 | N-(4-methoxy-phenyl)-2-cyclopentyl-...)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [3H]R-PIA from human adenosine A1 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50187672(CHEMBL207209 | N-(3,4-dichloro-phenyl)-2-cyclopent...)
Affinity DataKi:  4.69E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor in CHO membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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