TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.47E+5nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.94E+4nMAssay Description:Inhibition of mouse HCN2 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.55E+4nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.68E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.07E+5nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 9.41E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.83E+4nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.72E+4nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 3.13E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.31E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 4.52E+3nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 5.45E+3nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.46E+4nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.79E+4nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 7.23E+3nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 7.14E+3nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.49E+4nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 3.16E+4nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.04E+5nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 1.36E+5nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 7.07E+4nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 4.28E+3nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 8.57E+3nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 2.10E+4nMAssay Description:Inhibition of mouse HCN1 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 3.98E+3nMAssay Description:Inhibition of human HCN4 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Mus musculus)
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of HCN4 in C57BL/6J mouse thalamocortical relay neuron assessed as reduction in hyperpolarization current at holding potential of -120 mV ...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)
Curated by ChEMBL
Affinity DataEC50: 5.01E+4nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair