TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDE3A (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDE10A1 (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE4A1 (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of GST-tagged recombinant human PDE8A1More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of GST-tagged recombinant human PDE7A1More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
India Academy Of Scientific & Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant PI3K-deltaMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE3A (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of GST-tagged recombinant human PDE11A4More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of GST-tagged recombinant human PDE7A1More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE6C (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PDE2A1 (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human PDE5A1 expressed in baculovirus in sf9 cells by PDE Glo phosphodiesterase assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human PDE5A1 expressed in baculovirus in sf9 cells by PDE Glo phosphodiesterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PDE6C (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged recombinant human PDE11A4More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE5A1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of PDE2A1 (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Counsel Of Scientific & Industrial Research
US Patent
Counsel Of Scientific & Industrial Research
US Patent
Affinity DataIC50: 23nMAssay Description:PI3K inhibition assay (PI3K Assay (Emmanuelle M, Huang Y, Yan H G et al. Targeting Protein Translation in Human Non-Small Cell Lung Cancer via Combin...More data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human PDE5A1 expressed in baculovirus in sf9 cells by PDE Glo phosphodiesterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE5A1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute Of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of PDE1A1 (unknown origin) using fluorescently labeled cAMP substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair