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Found 35 with Last Name = 'scallen' and Initial = 'tj'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291237(CHEMBL153492 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  4.40nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291241(CHEMBL153021 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  6.30nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288124(Benzyl-{2-[4-((E)-styryl)-phenoxy]-ethyl}-amine | ...)
Affinity DataIC50:  9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288129((2-Phenyl-propyl)-{2-[4-((E)-styryl)-phenoxy]-ethy...)
Affinity DataIC50:  9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291258(CHEMBL152366 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  9.70nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288127(CHEMBL312125 | [2-(4-Benzyloxy-phenoxy)-ethyl]-(2-...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288123(CHEMBL82277 | [2-(4-Benzyloxy-phenoxy)-ethyl]-phen...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291255(CHEMBL358623 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  15nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291256(CHEMBL152129 | Sodium; (E)-(3R,5S)-7-[5-(4-chloro-...)
Affinity DataIC50:  21nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291252(CHEMBL152551 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  26nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291239(CHEMBL151961 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  26nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291243(CHEMBL152926 | Sodium; (E)-(3R,5S)-7-[4-(3-fluoro-...)
Affinity DataIC50:  49nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288128(Benzyl-(4-benzyloxy-benzyl)-amine | CHEMBL82015)
Affinity DataIC50:  55nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288125(Benzyl-[2-(4-benzyloxy-phenoxy)-ethyl]-amine | CHE...)
Affinity DataIC50:  70nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291251(CHEMBL346856 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  94nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291254(CHEMBL357515 | Sodium; (R)-3-hydroxy-7-[(1S,2S,8S,...)
Affinity DataIC50:  110nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291240(CHEMBL152032 | Sodium; (R)-7-[(1S,2S,6R,8S,8aR)-2,...)
Affinity DataIC50:  160nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291259(CHEMBL152893 | Sodium; (E)-(3R,5S)-7-(4-cyclohexyl...)
Affinity DataIC50:  202nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291248(CHEMBL358245 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  206nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291238(CHEMBL434313 | Sodium; (E)-(3R,5S)-7-[4-(2-fluoro-...)
Affinity DataIC50:  233nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291245(CHEMBL347277 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50:  325nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291249(CHEMBL348225 | Sodium; (E)-(3R,5S)-7-(4-cyclopenty...)
Affinity DataIC50:  417nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  530nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291247(CHEMBL154868 | Sodium; (E)-(3R,5S)-7-[5-cyclopenty...)
Affinity DataIC50:  570nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291260(CHEMBL154986 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  1.15E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291253(CHEMBL152114 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  1.42E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291246(CHEMBL346635 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  2.43E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291244(CHEMBL150649 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50:  2.98E+3nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291257(CHEMBL152963 | Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291250(CHEMBL358171 | Sodium; (E)-(3R,5S)-7-(4-biphenyl-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50291242(CHEMBL347095 | Sodium; (E)-(3R,5S)-3,5-dihydroxy-7...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288126(Benzyl-{2-[2-(4-benzyloxy-phenoxy)-ethoxy]-ethyl}-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288122(Benzyl-[2-(4-methoxy-phenoxy)-ethyl]-amine | CHEMB...)
Affinity DataIC50:  8.90E+4nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article