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Found 20 with Last Name = 'schaschke' and Initial = 'n'
TargetPepsin A(Porcine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50141614((1S,2S,5S)-3-Hydroxy-4-[2-((S)-hydroxy-6-(S)-4-{(S...)
Affinity DataKi:  0.0460nMAssay Description:Inhibitory activity of the compound against aspartyl protease pepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290289((S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoyl...)
Affinity DataKi:  1nMAssay Description:Equilibrium dissociation constant of the compound for the inhibition of human cathepsin B was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50141612((S)-4-[(S)-2-(2-Amino-2-methyl-butyrylamino)-3-met...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity of the compound against aspartyl protease pepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290289((S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoyl...)
Affinity DataKi:  3.40nMAssay Description:Equilibrium dissociation constant of the compound for the inhibition of human Mu-calpain was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112064(3-(3-Aminomethyl-phenyl)-2-(3-{2-[(2R,5S)-5-({2-[2...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50141613(3-{(R)-1-[(S,R)-1-((S)-2-{(S)-1-[1-((S)-2-Carboxy-...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity of the compound against aspartyl protease pepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112065(3-(3-Aminomethyl-phenyl)-2-[2-(2-{(2S,5R)-5-[({[2-...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112070(3-(3-Aminomethyl-phenyl)-2-{2-[2-((2R,5S)-5-{2-[2-...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112069(3-(3-Aminomethyl-phenyl)-2-(4-{2-[(2R,5S)-5-({3-[2...)
Affinity DataKi:  350nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112067(CHEMBL175811 | methyl3-(3-aminomethylphenyl)-2-{2-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112068((R)-2-Acetylamino-3-(3-aminomethyl-phenyl)-propion...)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50112066((R)-2-Acetylamino-3-(4-aminomethyl-phenyl)-propion...)
Affinity DataKi:  2.13E+5nMAssay Description:Inhibitory activity against human Tryptase beta was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  3.10E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  1.30E+6nMAssay Description:Inhibition of tissue kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  1.80E+6nMAssay Description:Inhibition of tissue kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359553(CHEMBL1927450)
Affinity DataKi:  2.00E+6nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Universit£T Bielefeld

Curated by ChEMBL
LigandPNGBDBM50359552(CHEMBL1927307)
Affinity DataKi:  3.30E+6nMAssay Description:Inhibition of plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed