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Found 21 with Last Name = 'scherf' and Initial = 'a'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant HDAC6 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581294(CHEMBL5076638)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant HDAC6 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50095120(CHEMBL3589752)
Affinity DataIC50:  25nMAssay Description:Inhibition of His-tagged human DHODH assessed as reduction of DCIP by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant HDAC6 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50:  60nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC3 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC2 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC3 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581294(CHEMBL5076638)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC3 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581294(CHEMBL5076638)
Affinity DataIC50:  140nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581294(CHEMBL5076638)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant HDAC1 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581291(CHEMBL5090521)
Affinity DataIC50:  160nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581292(CHEMBL5078298)
Affinity DataIC50:  210nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581293(CHEMBL5078990)
Affinity DataIC50:  230nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant HDAC2 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581294(CHEMBL5076638)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant HDAC2 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair